{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:04:03Z","timestamp":1773011043879,"version":"3.50.1"},"reference-count":39,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>The jaboticaba tree,<jats:italic>Plinia trunciflora<\/jats:italic>(O. Berg) Kausel, is popularly named \u201cjabuticabeira\u201d in Brazil and is used in folk medicine to treat diabetes and chronic inflammation of the tonsils, but studies evaluating the central effects of this species are limited. This study evaluated the antidepressant-like and antioxidant effects of<jats:italic>P. trunciflora<\/jats:italic>(PT) aqueous extract, in which five different anthocyanins were identified. PT showed significant ferric-reduction power and DPPH radical scavenging activity<jats:italic>in vitro<\/jats:italic>and reduced lipid peroxidation both<jats:italic>in vitro<\/jats:italic>and<jats:italic>ex vivo<\/jats:italic>. At the behavioural level, PT (400 and 800\u2009mg\/kg, i.p.) dose-dependently reduced immobility time in the tail suspension test in Swiss male mice. The identification of bioactive compounds accompanied by the<jats:italic>in vitro<\/jats:italic>and<jats:italic>ex vivo<\/jats:italic>antioxidant activity of PT suggests that these activities might be related to the antidepressant-like activity of<jats:italic>P. trunciflora<\/jats:italic>.<\/jats:p>","DOI":"10.1155\/2015\/601503","type":"journal-article","created":{"date-parts":[[2015,7,2]],"date-time":"2015-07-02T21:02:28Z","timestamp":1435870948000},"page":"1-9","source":"Crossref","is-referenced-by-count":23,"title":["Antidepressant-Like and Antioxidant Effects of<i>Plinia trunciflora<\/i>in Mice"],"prefix":"10.1155","volume":"2015","author":[{"given":"Cassia","family":"Sacchet","sequence":"first","affiliation":[{"name":"Programa de P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias Ambientais, Unochapec\u00f3, Avenida Senador Att\u00edlio Fontana 591E, 89809-000 Chapec\u00f3, SC, 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