{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T14:03:38Z","timestamp":1753884218978,"version":"3.41.2"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,2,16]],"date-time":"2015-02-16T00:00:00Z","timestamp":1424044800000},"content-version":"vor","delay-in-days":46,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Scientific World Journal"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. To evaluate whether a model to predict a failed endometrial biopsy in women with postmenopausal bleeding (PMB) and a thickened endometrium can reduce costs without compromising diagnostic accuracy. <jats:italic>Design, Setting, and Population<\/jats:italic>. Model based cost\u2010minimization analysis. <jats:italic>Methods<\/jats:italic>. A decision analytic model was designed to compare two diagnostic strategies for women with PMB: (I) attempting office endometrial biopsy and performing outpatient hysteroscopy after failed biopsy and (II) predicted probability of a failed endometrial biopsy based on patient characteristics to guide the decision for endometrial biopsy or immediate hysteroscopy. Robustness of assumptions regarding costs was evaluated in sensitivity analyses. <jats:italic>Main Outcome Measures<\/jats:italic>. Costs for the different strategies. <jats:italic>Results<\/jats:italic>. At different cut\u2010offs for the predicted probability of failure of an endometrial biopsy, strategy I was generally less expensive than strategy II. The costs for strategy I were always \u20ac 460; the costs for strategy II varied between \u20ac 457 and \u20ac 475. At a 65% cut\u2010off, a possible saving of \u20ac 3 per woman could be achieved. <jats:italic>Conclusions<\/jats:italic>. Individualizing the decision to perform an endometrial biopsy or immediate hysteroscopy in women presenting with postmenopausal bleeding based on patient characteristics does not increase the efficiency of the diagnostic work\u2010up.<\/jats:p>","DOI":"10.1155\/2015\/605312","type":"journal-article","created":{"date-parts":[[2015,2,16]],"date-time":"2015-02-16T21:02:34Z","timestamp":1424120554000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Does Probability Guided Hysteroscopy Reduce Costs in Women Investigated for Postmenopausal Bleeding?"],"prefix":"10.1155","volume":"2015","author":[{"given":"M. C.","family":"Breijer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"van Hanegem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N. C. M.","family":"Visser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. H. M.","family":"Verheijen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. W. J.","family":"Mol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. M. A.","family":"Pijnenborg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. C.","family":"Opmeer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Timmermans","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,2,16]]},"reference":[{"key":"e_1_2_6_1_2","doi-asserted-by":"publisher","DOI":"10.7863\/jum.2001.20.10.1025"},{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016349609033357"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.280.17.1510"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0029-7844(01)01771-9"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0b013e31819930cc"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0412.2004.00357.x"},{"key":"e_1_2_6_7_2","unstructured":"NVOG (Dutch Society of Obstetrics and Gynaecology) NVOG-richtlijn Abnormaal vaginaal bloedverlies in de menopauze 2003."},{"volume-title":"Investigation of Postmenopausal Bleeding","year":"2002","author":"Scottish Intercollegiate Guidelines Network","key":"e_1_2_6_8_2"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/aog.0b013e3181e3e7e8"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2010.11.010"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20001015)89:8<1765::AID-CNCR17>3.0.CO;2-F"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2006.00914.x"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2002.01088.x"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2007.05.040"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.12212"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828x.1999.tb03460.x"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2008.01773.x"},{"key":"e_1_2_6_18_2","unstructured":"Dutch Healtcare Authority (NZa) 2011 http:\/\/www.nza.nl\/."}],"container-title":["The Scientific World Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2015\/605312.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/tswj\/2015\/605312.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2015\/605312","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T01:49:00Z","timestamp":1722908940000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2015\/605312"}},"subtitle":[],"editor":[{"given":"Eun-Kyoung","family":"Breuer","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["10.1155\/2015\/605312"],"URL":"https:\/\/doi.org\/10.1155\/2015\/605312","archive":["Portico"],"relation":{},"ISSN":["2356-6140","1537-744X"],"issn-type":[{"type":"print","value":"2356-6140"},{"type":"electronic","value":"1537-744X"}],"subject":[],"published":{"date-parts":[[2015,1]]},"assertion":[{"value":"2014-07-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-12-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-02-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"605312"}}