{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T12:01:07Z","timestamp":1722945667355},"reference-count":19,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Gastrointestinal Medicine"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Cicatricial pemphigoid (CP) is a rare blistering autoimmune disease. Esophageal involvement occurs in widespread disease and rarely appears as the only affected organ. We report a 67-year-old Caucasian female with esophageal dysphagia and weight loss. Several oral panendoscopies showed multiple exudative ulcerations with fibrin and webs in mid- and proximal esophagus and a peeling mucosa. There were no lesions in other organs. We established the diagnosis performing a direct immunofluorescence (DIF), demonstrating IgG3 and complement deposition along the basement membrane. As initial treatment the patient received prednisone 60\u2009mg and 1\u2009gr twice daily of mycophenolate mofetil (MMF) as a steroid-sparing agent due to its lower toxicity and its selective mechanism of action. Six months later there was a significant clinical improvement and the esophageal ulcerations had disappeared, developing cicatricial fibrous rings, although no stenosis was present. Four years later, the patient remains asymptomatic with a low maintenance dose of MMF.<\/jats:p>","DOI":"10.1155\/2015\/620374","type":"journal-article","created":{"date-parts":[[2015,10,18]],"date-time":"2015-10-18T17:02:57Z","timestamp":1445187777000},"page":"1-4","source":"Crossref","is-referenced-by-count":1,"title":["Esophageal Cicatricial Pemphigoid as an Isolated Involvement Treated with Mycophenolate Mofetil"],"prefix":"10.1155","volume":"2015","author":[{"given":"Sandra","family":"S\u00e1nchez Prudencio","sequence":"first","affiliation":[{"name":"Gastroenterology Department, Hospital Infanta Cristina, Avenida 9 de Junio, No. 2, 28981 Parla, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Domingo Senra","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, Hospital Infanta Cristina, Avenida 9 de Junio, No. 2, 28981 Parla, Madrid, 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