{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T02:38:12Z","timestamp":1761964692457,"version":"3.37.3"},"reference-count":16,"publisher":"Wiley","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Although lymphoma may occasionally involve the adrenal glands as part of a generalized disease process, primary adrenal lymphoma (PAL) is a rare disease. We present a case of a 62-year-old woman with a history of mild\/moderate hereditary spherocytosis with a well-compensated baseline haemoglobin, who presented with rapidly progressive symptomatic anaemia. During the diagnostic workup, imaging revealed bilateral large adrenal masses and she was later diagnosed with diffuse large B-cell non-Hodgkin\u2019s lymphoma (DLBCL), with the adrenal glands being the dominant site of the disease. The patient was started on systemic chemotherapy, but her disease progressed with neurological involvement which responded to second-line therapy. Her adrenal disease however was refractory to further therapy.<\/jats:p>","DOI":"10.1155\/2015\/620381","type":"journal-article","created":{"date-parts":[[2015,11,22]],"date-time":"2015-11-22T16:01:42Z","timestamp":1448208102000},"page":"1-6","source":"Crossref","is-referenced-by-count":8,"title":["Primary Bilateral Non-Hodgkin\u2019s Lymphoma of the Adrenal Gland Presenting as Incidental Adrenal Masses"],"prefix":"10.1155","volume":"2015","author":[{"given":"Christopher","family":"Rizzo","sequence":"first","affiliation":[{"name":"Diabetes and Endocrine Centre, Mater Dei Hospital, Msida MSD 2090, Malta"},{"name":"Department of Medicine, University of Malta Medical School, Msida MSD 2080, Malta"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David James","family":"Camilleri","sequence":"additional","affiliation":[{"name":"Department of Haemato-Oncology, Mater Dei Hospital, Msida MSD 2090, Malta"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0690-4257","authenticated-orcid":true,"given":"Alexandra","family":"Betts","sequence":"additional","affiliation":[{"name":"Histopathology Section, Pathology Department, Mater Dei Hospital, Msida MSD 2090, Malta"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andre\u2019","family":"Gatt","sequence":"additional","affiliation":[{"name":"Medical Imaging Department, Mater Dei Hospital, Msida MSD 2090, Malta"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2372-7101","authenticated-orcid":true,"given":"Stephen","family":"Fava","sequence":"additional","affiliation":[{"name":"Diabetes and Endocrine Centre, Mater Dei Hospital, Msida MSD 2090, Malta"},{"name":"Department of Medicine, University of Malta Medical School, Msida MSD 2080, Malta"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197201)29:160;252::aid-cncr282029013862;3.0.co;2-35;"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199309303291402"},{"issue":"1-2","key":"3","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3109\/10428199909083386","volume":"34","year":"1999","journal-title":"Leukemia and Lymphoma"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.3816\/clm.2003.n.024"},{"issue":"5-6","key":"5","doi-asserted-by":"crossref","first-page":"543","DOI":"10.3109\/10428199709058323","volume":"27","year":"1997","journal-title":"Leukemia and Lymphoma"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19930615)71:12<4030::AID-CNCR2820711237>3.0.CO;2-Q"},{"issue":"3-4","key":"7","doi-asserted-by":"crossref","first-page":"363","DOI":"10.3109\/10428199709039025","volume":"24","year":"1997","journal-title":"Leukemia and Lymphoma"},{"issue":"4","key":"8","first-page":"298","volume":"14","year":"1999","journal-title":"Annali Italiani di Medicina Interna"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(02)01681-1"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.4103\/2230-8210.85604"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1589"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1182\/blood.v99.11.3909"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-013-1812-3"},{"key":"14","first-page":"130","volume":"58","year":"1998","journal-title":"Hematology"},{"issue":"5","key":"15","first-page":"534","volume":"9","year":"1996","journal-title":"Modern Pathology"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2009.87"}],"container-title":["Case Reports in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2015\/620381.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2015\/620381.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2015\/620381.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,23]],"date-time":"2017-06-23T20:09:42Z","timestamp":1498248582000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crim\/2015\/620381\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":16,"alternative-id":["620381","620381"],"URL":"https:\/\/doi.org\/10.1155\/2015\/620381","relation":{},"ISSN":["1687-9627","1687-9635"],"issn-type":[{"type":"print","value":"1687-9627"},{"type":"electronic","value":"1687-9635"}],"subject":[],"published":{"date-parts":[[2015]]}}}