{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T22:54:50Z","timestamp":1787612090473,"version":"build-2736575974"},"reference-count":13,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Infectious Diseases"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Typhoid fever is one of the few bacterial infections in humans where bone marrow evaluation is routinely recommended. However, the morphological aspect of typhoid fever in bone marrow has been rarely described in the literature. We describe a 25-year-old male patient who presented with prolonged fever suspected to be of tubercular etiology. Bone marrow examination showed well-formed histiocytic and epithelioid granulomas and erythrophagocytosis; and the bone marrow aspirate culture grew<jats:italic>Salmonella typhi<\/jats:italic>A. In view of potential clinical implications, typhoid fever should be considered as a differential diagnosis to tuberculosis in the evaluation of prolonged fever; especially in high prevalent areas. We suggest that erythrophagocytosis may serve as a morphological marker in typhoid granulomas in the bone marrow; and bone marrow culture should be submitted in every suspected case for appropriate patient management.<\/jats:p>","DOI":"10.1155\/2015\/628028","type":"journal-article","created":{"date-parts":[[2015,2,19]],"date-time":"2015-02-19T16:02:42Z","timestamp":1424361762000},"page":"1-6","source":"Crossref","is-referenced-by-count":5,"title":["Bone Marrow Granuloma in Typhoid Fever: A Morphological Approach and Literature Review"],"prefix":"10.1155","volume":"2015","author":[{"given":"Kavitha","family":"Muniraj","sequence":"first","affiliation":[{"name":"Department of Pathology, Pondicherry Institute of Medical Sciences, Puducherry 605014, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Somanath","family":"Padhi","sequence":"additional","affiliation":[{"name":"Department of Pathology, Pondicherry Institute of Medical Sciences, Puducherry 605014, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manjiri","family":"Phansalkar","sequence":"additional","affiliation":[{"name":"Department of Pathology, Pondicherry Institute of Medical Sciences, Puducherry 605014, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Periyasami","family":"Sivakumar","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Pondicherry Institute of Medical Sciences, Puducherry 605014, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renu G\u2019Boy","family":"Varghese","sequence":"additional","affiliation":[{"name":"Department of Pathology, Pondicherry Institute of Medical Sciences, Puducherry 605014, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reba","family":"Kanungo","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Pondicherry Institute of Medical Sciences, Puducherry 605014, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","reference":[{"key":"1","year":"2010"},{"issue":"1","key":"2","first-page":"13","volume":"48","year":"2005","journal-title":"Indian Journal of Pathology and Microbiology"},{"issue":"1","key":"3","first-page":"57","volume":"9","year":"2004","journal-title":"Journal of Korean Medical Science"},{"key":"4","first-page":"462","volume":"20","year":"1986","journal-title":"The Korean Journal of Pathology"},{"key":"5","first-page":"515","volume":"5","year":"1985","journal-title":"Journal of Clinical Pathology"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1097\/00043426-200112000-00015"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.43.436"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2004.05157"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1159\/000204357"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.0030193"},{"issue":"4","key":"12","first-page":"248","volume":"47","year":"2001","journal-title":"Journal of Postgraduate Medicine"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.3343\/kjlm.2007.27.3.182"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.39.4.1571-1576.2001"}],"container-title":["Case Reports in Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criid\/2015\/628028.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criid\/2015\/628028.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criid\/2015\/628028.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,18]],"date-time":"2016-08-18T18:40:47Z","timestamp":1471545647000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/criid\/2015\/628028\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":13,"alternative-id":["628028","628028"],"URL":"https:\/\/doi.org\/10.1155\/2015\/628028","relation":{},"ISSN":["2090-6625","2090-6633"],"issn-type":[{"value":"2090-6625","type":"print"},{"value":"2090-6633","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}