{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T22:24:28Z","timestamp":1782253468197,"version":"3.54.5"},"reference-count":17,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>The application of histology to soft tissue remains offers an important technique to obtain diagnostically important information on various physiological and pathological conditions in paleopathology. In a series of 29 cases with mummified tissue ranging between 16 months and c. 5.200 years of postmortem time interval, we systematically investigated paleohistology and the preservation of various tissues. We established a reproducible histological ranking system for the evaluation of mummified tissue preservation. The application of this scheme to the series showed good tissue preservation of tissues with high connective tissue content but also fat tissue and connective tissue rich organs, such as lung tissue, while most other internal organs were less well preserved despite highly different postmortem time intervals. There are some organs with only poor conservation even in short term periods such as the kidneys and CNS. Artificial mummification does not provide better conservation than naturally mummified tissues; \u201ccold\u201d mummies may be much better conserved than those from desert areas. The identification of specific pathologies underlines the potential power of paleohistology.<\/jats:p>","DOI":"10.1155\/2015\/631465","type":"journal-article","created":{"date-parts":[[2015,8,6]],"date-time":"2015-08-06T21:09:16Z","timestamp":1438895356000},"page":"1-9","source":"Crossref","is-referenced-by-count":12,"title":["A Systematic Approach to the Application of Soft Tissue Histopathology in Paleopathology"],"prefix":"10.1155","volume":"2015","author":[{"given":"Christina","family":"Grove","sequence":"first","affiliation":[{"name":"Institute of Legal Medicine, Ludwig-Maximilians University of Munich, 80336 Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver","family":"Peschel","sequence":"additional","affiliation":[{"name":"Institute of Legal Medicine, Ludwig-Maximilians University of Munich, 80336 Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas G.","family":"Nerlich","sequence":"additional","affiliation":[{"name":"Division of Paleopathology, Institute of Pathology, Academic Clinic Munich-Bogenhausen and Munich-Schwabing, 81925 Munich, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.20.2571"},{"issue":"2557","key":"2","first-page":"16","volume":"1","year":"1910","journal-title":"The British Medical Journal"},{"key":"3","year":"1979"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1126\/science.1090004"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0089528"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-010-0842-z"},{"issue":"4","key":"7","first-page":"423","volume":"427","year":"1995","journal-title":"Virchows Archiv"},{"key":"8","first-page":"83","volume":"9","year":"1997","journal-title":"Journal of Paleopathology"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(03)13992-x"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-009-1409-4"},{"issue":"2521, article 1005","key":"11","volume":"1","year":"1909","journal-title":"The British Medical Journal"},{"issue":"6","key":"12","doi-asserted-by":"crossref","first-page":"277","DOI":"10.3109\/10520295509114479","volume":"30","year":"1955","journal-title":"Stain technology"},{"key":"13","volume":"69, article 471","year":"1985","journal-title":"Verhandlungen der Deutschen Gesellschaft f\u00fcr Pathologie"},{"key":"14","first-page":"347","volume-title":"Histology and histopathology of the Manchester mummies","year":"1986"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1080\/10520290500051146"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.2307\/2529310"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.20728"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/631465.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/631465.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/631465.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,23]],"date-time":"2017-06-23T17:08:45Z","timestamp":1498237725000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/bmri\/2015\/631465\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":17,"alternative-id":["631465","631465"],"URL":"https:\/\/doi.org\/10.1155\/2015\/631465","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}