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The total flavonoid and phenolic contents as well as extraction yield of the extracts were also investigated to determine their correlation with the antioxidant activity of the extracts. Among all the tested extracts the highest amounts of total phenolic and total flavonoids content were found in methanol extract of<jats:italic>in vivo<\/jats:italic>grown plants. The antioxidant activity of tested samples followed the order<jats:italic>in vivo<\/jats:italic>plant extract &gt; callus extract &gt;<jats:italic>in vitro<\/jats:italic>extract. The highest reducing power, 2,2-azino-bis-(3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) radical scavenging, and chelating power were found in methanol extracts of<jats:italic>in vivo<\/jats:italic>grown red clover, while the chloroform fraction of<jats:italic>in vivo<\/jats:italic>grown plants showed the highest 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, superoxide anion radical scavenging and hydrogen peroxide scavenging compared to the other tested extracts. A significant correlation was found between the antioxidant activity of extracts and their total phenolic and total flavonoid content. According to the findings, the extract of<jats:italic>in vitro<\/jats:italic>culture of red clover especially the callus tissue possesses a comparable antioxidant activity to the<jats:italic>in vivo<\/jats:italic>cultured plants\u2019 extract.<\/jats:p>","DOI":"10.1155\/2015\/643285","type":"journal-article","created":{"date-parts":[[2015,5,6]],"date-time":"2015-05-06T17:02:45Z","timestamp":1430931765000},"page":"1-11","source":"Crossref","is-referenced-by-count":150,"title":["Antioxidant Activity and Total Phenolic and Flavonoid Content of Various Solvent Extracts from<i>In Vivo<\/i>and<i>In Vitro<\/i>Grown<i>Trifolium pratense<\/i>L. 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