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There is limited information about its pharmacological properties, and few studies in humans concern its acute and chronic effects. 2C-B has been classified as a stimulant, hallucinogen, entactogen, and\/or empathogen.<jats:italic>Objectives<\/jats:italic>. To evaluate the emotional, subjective, and cardiovascular effects of 2C-B.<jats:italic>Methods<\/jats:italic>. Twenty healthy recreational 2C-B users (12 women) self-administered a 20\u2009mg dose of 2C-B. Evaluations included emotional (IAPS, FERT, and speech), subjective (visual analog scales, ARCI, VESSPA, HRS, and POMS questionnaires), and cardiovascular effects (blood pressure and heart rate).<jats:italic>Results<\/jats:italic>. Positive subjective effects predominated with a reduction of anger under the influence of 2C-B. It did, however, increase reactivity to negative emotional stimuli and decrease the ability to recognize expressions of happiness. Augmented emotionality in speech could be appreciated by others. 2C-B induced euphoria and well-being, changes in perceptions, and slight hallucinogenic states. Mild sympathetic actions were observed.<jats:italic>Conclusions<\/jats:italic>. The specific profile that 2C-B exerts on emotions suggests its classification as an entactogen with psychedelic properties.<\/jats:p>","DOI":"10.1155\/2015\/643878","type":"journal-article","created":{"date-parts":[[2015,10,13]],"date-time":"2015-10-13T18:45:58Z","timestamp":1444761958000},"page":"1-9","source":"Crossref","is-referenced-by-count":35,"title":["Acute Effects of the Novel Psychoactive Drug 2C-B on Emotions"],"prefix":"10.1155","volume":"2015","author":[{"given":"D\u00e9bora","family":"Gonz\u00e1lez","sequence":"first","affiliation":[{"name":"Department of Pharmacology and Department of Psychiatry, Universitat Aut\u00f2noma de Barcelona, Doctor Aiguader 80, 08003 Barcelona, Spain"},{"name":"Hospital del Mar Medical Research Institute (IMIM), Doctor Aiguader 88, 08003 Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Torrens","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Department of 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