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Sperm count was also reduced by 64.7 and 89.9% in prepubertal rats and 64.9 and 47.0% in adult rats, respectively. Nicotine decreased sperm motility (82.2%) and count (62.6%) in prepubertal rats but caused no effect in adult rats. There were no changes in sperm morphology; testosterone was decreased, while LH and FSH were increased in exposed rats, when compared with control. Malondialdehyde levels in testes of exposed rats were increased, and GSH, SOD, and catalase were altered. Results indicate that subacute exposure of tobacco products alters sperm characteristics in a rank order of ST &gt; TS &gt; nicotine, which may be linked to increase in oxidative stress in the testis.<\/jats:p>","DOI":"10.1155\/2015\/676245","type":"journal-article","created":{"date-parts":[[2015,11,8]],"date-time":"2015-11-08T21:02:03Z","timestamp":1447016523000},"page":"1-10","source":"Crossref","is-referenced-by-count":9,"title":["Comparative Evaluation of the Impact of Subacute Exposure of Smokeless Tobacco and Tobacco Smoke on Rat Testis"],"prefix":"10.1155","volume":"2015","author":[{"given":"Jonah Sydney","family":"Aprioku","sequence":"first","affiliation":[{"name":"Department of Pharmacology, Faculty of Basic Medical Sciences, University of Port Harcourt, PMB 5323, Port Harcourt, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa Chioma","family":"Ugwu","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Faculty of Basic 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