{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T18:22:35Z","timestamp":1783707755306,"version":"3.55.0"},"reference-count":14,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Ophthalmological Medicine"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p><jats:italic>Purpose<\/jats:italic>. To report a rare presentation of culture positive<jats:italic>Mycobacterium chelonae<\/jats:italic>(<jats:italic>M. chelonae<\/jats:italic>) corneal ulcer and its management.<jats:italic>Case Report<\/jats:italic>. We report a rare case with history of chronic pain and blurriness of vision. Examination revealed chronic nonhealing paracentral corneal ulcer inferiorly at 5 to 7 o\u2019clock meridian with anterior chamber cells 1+ unresponsive to routine antibiotic and antifungal medications with Mantoux test (MT) positivity in a middle aged nondiabetic patient with no prior obvious history of trauma, ocular surgery, and contact lens usage.<jats:italic>Discussion<\/jats:italic>. Ziehl Neelsen (ZN) staining in nonhealing ulcer revealed acid fast bacilli typical of<jats:italic>M. chelonae<\/jats:italic>with subsequent culture positivity in Lowenstein Jensen (LJ) medium. Subsequent treatment with topical fortified amikacin and tobramycin resulted in rapid healing of corneal ulcer.<jats:italic>Conclusion. M. chelonae<\/jats:italic>presenting as a chronic nonhealing corneal ulcer spontaneously occurring in a healthy young adult with no predisposing factor draws the need to have a good index of suspicion by performing ZN stain and culture and its subsequent successful management with topical fortified amikacin and tobramycin.<\/jats:p>","DOI":"10.1155\/2015\/708312","type":"journal-article","created":{"date-parts":[[2015,12,22]],"date-time":"2015-12-22T21:02:21Z","timestamp":1450818141000},"page":"1-3","source":"Crossref","is-referenced-by-count":1,"title":["An Unusual Case of Nonhealing Granulomatous Keratitis Caused by<i>Mycobacterium chelonae<\/i>in a Healthy Middle Aged Adult"],"prefix":"10.1155","volume":"2015","author":[{"given":"Vipul","family":"Bhandari","sequence":"first","affiliation":[{"name":"Department of Cornea, Nethradhama Eye Hospital, Bengaluru 560070, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Sriganesh","sequence":"additional","affiliation":[{"name":"Department of Cornea, Nethradhama Eye Hospital, Bengaluru 560070, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirti","family":"Relekar","sequence":"additional","affiliation":[{"name":"Department of Cornea, Nethradhama Eye Hospital, Bengaluru 560070, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","reference":[{"key":"1","first-page":"1033","volume-title":"Nontuberculous mycobacterial disease","year":"1996"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1097\/ico.0b013e31826cf840"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2009.160853"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2005.069856"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.survophthal.2011.10.006"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/164989"},{"issue":"1","key":"7","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0025-7125(16)34193-1","volume":"43","year":"1959","journal-title":"The Medical Clinics of North America"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2011.02679.x"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9394(01)01267-3"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(02)01643-3"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2010.11.034"},{"issue":"4","key":"12","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0255-0857(21)02768-7","volume":"22","year":"2004","journal-title":"Indian Journal of Medical Microbiology"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.80.11.962"},{"issue":"4","key":"14","first-page":"228","volume":"28","year":"2002","journal-title":"CLAO Journal"}],"container-title":["Case Reports in Ophthalmological Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2015\/708312.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2015\/708312.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criopm\/2015\/708312.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,5,30]],"date-time":"2022-05-30T12:24:02Z","timestamp":1653913442000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/criopm\/2015\/708312\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":14,"alternative-id":["708312","708312"],"URL":"https:\/\/doi.org\/10.1155\/2015\/708312","relation":{},"ISSN":["2090-6722","2090-6730"],"issn-type":[{"value":"2090-6722","type":"print"},{"value":"2090-6730","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}