{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T14:25:45Z","timestamp":1780064745858,"version":"3.54.0"},"reference-count":21,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Biomaterials"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Bone defects following tumor resection and osteolysis due to bone lesions, periodontal tissue disorders, and bone reconstruction are challenges that surgeons face. Gass-ceramic-chitosan nanocomposite contains chitosan, a derivative of crustaceans\u2019 exoskeleton.<jats:italic>Methods<\/jats:italic>. Thirty-two 6\u20138-week-old male Wistar rats were chosen. One hole on each right and left tibia was made. The right tibia holes were filled with injectable glass-ceramic-chitosan nanocomposite, and the left tibia holes were left empty. After 7, 14, 28, and 60 days, histopathological, histomorphometrical, and radiographical assessments were performed.<jats:italic>Results<\/jats:italic>. Radiographic density on days 7 and 14 was significantly higher in the right tibias than in the left tibias. Trabecular bone thickness, which was higher in the right tibias, increased from day 7 to day 60 in both right and left tibias, although not significantly.<jats:italic>Conclusions<\/jats:italic>. Glass-ceramic-chitosan nanocomposite is suggested for use in bone repair in cases of bone loss. More histopathological, histomorphometrical, and radiographical assessments are also recommended.<\/jats:p>","DOI":"10.1155\/2015\/719574","type":"journal-article","created":{"date-parts":[[2015,2,8]],"date-time":"2015-02-08T21:01:41Z","timestamp":1423429301000},"page":"1-8","source":"Crossref","is-referenced-by-count":5,"title":["Histopathological, Histomorphometrical, and Radiographical Evaluation of Injectable Glass-Ceramic-Chitosan Nanocomposite in Bone Reconstruction of Rat"],"prefix":"10.1155","volume":"2015","author":[{"given":"Maryam","family":"Seyedmajidi","sequence":"first","affiliation":[{"name":"Dental Materials Research Center, School of Dentistry, Babol University of Medical Sciences, Babol, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyedmahmood","family":"Rabiee","sequence":"additional","affiliation":[{"name":"Department of Materials Engineering, School of Mechanic Engineering, Babol University of Technology, Babol, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sina","family":"Haghanifar","sequence":"additional","affiliation":[{"name":"Oral & Maxillofacial Radiology Department, School of Dentistry, Babol University of Medical Sciences, Babol, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyedkamal","family":"Seyedmajidi","sequence":"additional","affiliation":[{"name":"Department of Materials Engineering, School of Mechanic Engineering, Babol University of Technology, Babol, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seyed Gholam ali","family":"Jorsaraei","sequence":"additional","affiliation":[{"name":"Fatemeh Zahra Infertility and Reproductive Health Research Center, School of Medicine, Babol University of Medical Sciences, Babol, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Homayoun","family":"Alaghehmand","sequence":"additional","affiliation":[{"name":"Operative Dentistry Department, School of Dentistry, Babol University of Medical Sciences, Babol, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naghmeh","family":"Jamaatlu","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, School of Dentistry, Babol University of Medical Sciences, Babol, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Bijani","sequence":"additional","affiliation":[{"name":"Non-communicable Pediatrics Disease Research Center, Babol University of Medical Sciences, Babol, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(00)00191-5"},{"key":"2","first-page":"63","volume-title":"Bioactive glasses: clinical applications","year":"1993"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnoncrysol.2008.05.031"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2009.11.030"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1002\/macp.1985.021860815"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2006.06.021"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1021\/bm034130m"},{"issue":"4","key":"8","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1002\/1097-4636(20000915)51:4<586::AID-JBM6>3.0.CO;2-S","volume":"51","year":"2000","journal-title":"Journal of Biomedical Materials Research"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1007\/s10856-009-3885-z"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1007\/s10856-007-3329-6"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2007.03.013"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/s0736-0266(03)00082-2"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1002\/term.5"},{"issue":"110","key":"14","first-page":"200","volume":"23","year":"2014","journal-title":"Journal of Mazandaran University of Medical Sciences"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.proghi.2007.06.001"},{"key":"16","year":"2010"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/s8756-3282(99)00135-0"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1002\/term.5"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/s0142-9612(99)00143-x"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2007.04.006"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2006.08.007"}],"container-title":["International Journal of Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijbm\/2015\/719574.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijbm\/2015\/719574.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ijbm\/2015\/719574.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,23]],"date-time":"2017-06-23T05:11:23Z","timestamp":1498194683000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/ijbm\/2015\/719574\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":21,"alternative-id":["719574","719574"],"URL":"https:\/\/doi.org\/10.1155\/2015\/719574","relation":{},"ISSN":["1687-8787","1687-8795"],"issn-type":[{"value":"1687-8787","type":"print"},{"value":"1687-8795","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}