{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T16:13:50Z","timestamp":1788365630109,"version":"build-2803163510"},"reference-count":39,"publisher":"Wiley","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U1301213"],"award-info":[{"award-number":["U1301213"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Curcuminoids, and mainly curcumin, are potential therapeutic agents for the prevention of various diseases; however, little is known about the factors that influence their accumulation in<jats:italic>Curcuma<\/jats:italic>species. In this study, the effects of factors such as sucrose concentration, different ratios of 6-benzylaminopurine (6-BA) and<jats:italic>\u03b1<\/jats:italic>-naphthalene acetic acid (NAA), and light quality on the accumulation of curcumin and other curcuminoids in<jats:italic>Curcuma aromatica<\/jats:italic>were investigated. Microrhizomes grown on media containing 3% sucrose produced more curcumin and other curcuminoids than those grown on higher concentrations. Moreover, when compared to other ratios of 6-BA and NAA, microrhizomes induced on 3% sucrose media supplemented with 3.0\u2009mg\/L 6-BA and 0.5\u2009mg\/L NAA produced more curcumin and other curcuminoids; however, the amount was less than in microrhizomes grown on 3% sucrose alone. We determined that a 5% sucrose medium supplemented with 3.0\u2009mg\/L of 6-BA and 0.5\u2009mg\/L of NAA enhanced the levels of curcumin and curcuminoids and that exposure to red light further increased production.<\/jats:p>","DOI":"10.1155\/2015\/740794","type":"journal-article","created":{"date-parts":[[2015,2,2]],"date-time":"2015-02-02T16:21:20Z","timestamp":1422894080000},"page":"1-10","source":"Crossref","is-referenced-by-count":13,"title":["Factors Affecting the Accumulation of Curcumin in Microrhizomes of<i>Curcuma aromatica<\/i>Salisb"],"prefix":"10.1155","volume":"2015","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7639-3221","authenticated-orcid":true,"given":"Ke","family":"Wu","sequence":"first","affiliation":[{"name":"Guangdong Key Lab of Biotechnology for Plant Development, College of Life Sciences, South China Normal University, Guangzhou, Guangdong 510631, 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