{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T01:11:34Z","timestamp":1653527494467},"reference-count":43,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Endocrinology"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Hungry Bone Syndrome refers to the severe and prolonged hypocalcemia and hypophosphatemia, following parathyroidectomy in patients with hyperparathyroidism. We present the case of an eighteen-year-old woman with a four-year history of hyporexia, polydipsia, weight loss, growth retardation, and poor academic performance. The diagnostic work-up demonstrated primary hyperparathyroidism with hypercalcemia of 13.36\u2009mg\/dL, a PTH level of 2551\u2009pg\/mL, bone brown tumors, and microcalcifications within pancreas and kidneys. Neck ultrasonography revealed a parathyroid adenoma of 33 \u00d7 14 \u00d7 14\u2009mm, also identified on<jats:sup>99<\/jats:sup>Tc-sestamibi scan. Bone densitometry showed decreased<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>Z<\/mml:mi><\/mml:mrow><\/mml:math>-Score values (total lumbar<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mi>Z<\/mml:mi><\/mml:mrow><\/mml:math>-Score of \u22124.2). A right hemithyroidectomy and right lower parathyroidectomy were performed. Pathological examination showed an atypical parathyroid adenoma, of 3.8\u2009g of weight and 2.8\u2009cm in diameter. After surgery she developed hypocalcemia with tetany and QTc interval prolongation. The patient required 3 months of oral and intravenous calcium supplementation due to Hungry Bone Syndrome (HBS). After 42 months, she is still under oral calcium. Usually HBS lasts less than 12 months. Therefore we propose the term \u201cProtracted HBS\u201d in patients with particularly long recovery of 1 year. We present a literature review of the diagnosis, pathophysiology, and treatment of HBS.<\/jats:p>","DOI":"10.1155\/2015\/757951","type":"journal-article","created":{"date-parts":[[2015,11,12]],"date-time":"2015-11-12T21:01:24Z","timestamp":1447362084000},"page":"1-8","source":"Crossref","is-referenced-by-count":0,"title":["Atypical Parathyroid Adenoma Complicated with Protracted Hungry Bone Syndrome after Surgery: A Case Report and Literature Review"],"prefix":"10.1155","volume":"2015","author":[{"given":"\u00d3scar Alfredo","family":"Ju\u00e1rez-Le\u00f3n","sequence":"first","affiliation":[{"name":"Endocrinology and Metabolism Department, Instituto Nacional de Ciencias M\u00e9dicas y Nutrici\u00f3n Salvador Zubir\u00e1n, 14080 Mexico City, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel \u00c1ngel","family":"G\u00f3mez-S\u00e1mano","sequence":"additional","affiliation":[{"name":"Endocrinology and Metabolism Department, Instituto Nacional de Ciencias 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