{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T15:53:15Z","timestamp":1790610795008,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,8,3]],"date-time":"2015-08-03T00:00:00Z","timestamp":1438560000000},"content-version":"vor","delay-in-days":214,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"National Science Centre in Poland","award":["NN402 472637"],"award-info":[{"award-number":["NN402 472637"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Mediators of Inflammation"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:p>\n                    <jats:italic>Objectives.<\/jats:italic>\n                    To assess serum interleukin\u20106 (IL\u20106) and interleukin\u201023 (IL\u201023) and their correlation with angiogenic cytokines and disease activity in ankylosing spondylitis (AS), psoriatic arthritis (PsA), and SAPHO syndrome.\n                    <jats:italic>Patients and Methods.<\/jats:italic>\n                    We studied 152 spondyloarthritis (SpA) patients: 69 PsA, 61 AS, 22 SAPHO, and 29 controls. We recorded age, sex, disease duration, and treatment. We assessed BASDAI, VAS, and PASI scores. Serum IL\u20106, IL\u201023, VEGF, EGF, FGFb, and FGFa levels were determined using ELISA. We estimated ESR and CRP.\n                    <jats:italic>Results.<\/jats:italic>\n                    Serum IL\u20106 and IL\u201023 levels were higher in SpA than in control (\n                    <jats:italic>P<\/jats:italic>\n                    &lt; 0.00001 and\n                    <jats:italic>P<\/jats:italic>\n                    = 0.0004, resp.). There was a positive correlation between serum IL\u20106 and CRP in AS (\n                    <jats:italic>P<\/jats:italic>\n                    = 0.000001), PsA (\n                    <jats:italic>P<\/jats:italic>\n                    = 0.000001), and SAPHO (\n                    <jats:italic>P<\/jats:italic>\n                    = 0.0003) patients. There was a positive correlation between serum IL\u20106 and ESR in AS (\n                    <jats:italic>P<\/jats:italic>\n                    = 0.000001), PsA (\n                    <jats:italic>P<\/jats:italic>\n                    = 0.002), and SAPHO (\n                    <jats:italic>P<\/jats:italic>\n                    = 0.02) patients. There was no correlation of serum IL\u20106 and IL\u201023 with VAS, BASDAI, and angiogenic cytokines in SpA.\n                    <jats:italic>Conclusions.<\/jats:italic>\n                    Serum IL\u20106 but not serum IL\u201023 correlated with ESR and CRP in SpA. No correlation was found of serum IL\u20106 and IL\u201023 with VAS, BASDAI, and angiogenic cytokines.\n                  <\/jats:p>","DOI":"10.1155\/2015\/785705","type":"journal-article","created":{"date-parts":[[2015,8,4]],"date-time":"2015-08-04T02:28:58Z","timestamp":1438655338000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":54,"title":["Serum IL\u20106 and IL\u201023 Levels and Their Correlation with  Angiogenic Cytokines and Disease Activity in Ankylosing Spondylitis, Psoriatic Arthritis, and SAPHO Syndrome"],"prefix":"10.1155","volume":"2015","author":[{"given":"Hanna","family":"Przepiera-B\u0119dzak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarzyna","family":"Fischer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Brzosko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,8,3]]},"reference":[{"key":"e_1_2_9_1_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/33.10.927"},{"key":"e_1_2_9_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-006-0283-5"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2010.129148"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-010-1646-5"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2008.03.004"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.30600"},{"key":"e_1_2_9_7_2","first-page":"15","article-title":"Th17 and interleukin 23 in the pathogenesis of psoriatic arthritis and spondyloarthritis","volume":"39","author":"Cauli A.","year":"2012","journal-title":"Journal of Rheumatology"},{"key":"e_1_2_9_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-008-1011-0"},{"key":"e_1_2_9_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2009.107649"},{"key":"e_1_2_9_10_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1563-258x.2002.01118.x"},{"key":"e_1_2_9_11_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2249.2003.02101.x"},{"key":"e_1_2_9_12_2","first-page":"305","article-title":"Vascular endothelial growth factor in patients with psoriatic arthritis","volume":"25","author":"Fink A. 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