{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T13:57:37Z","timestamp":1761400657015},"reference-count":15,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p><jats:italic>Objective.<\/jats:italic>To evaluate the forward shifting of cervical spinal cords in different segments of patients with Hirayama disease to determine whether the disease is self-limiting.<jats:italic>Methods.<\/jats:italic>This study was performed on 11 healthy subjects and 64 patients. According to the duration, the patients were divided into 5 groups (\u22641 year, 1-2 years, 2-3 years, 3-4 years, and \u22654 years). Cervical magnetic resonance imaging (MRI) of flexion and conventional position was performed. The distances between the posterior edge of the spinal cord and the cervical spinal canal (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>X<\/mml:mi><\/mml:mrow><\/mml:math>), the anterior and posterior wall of the cervical spinal canal (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mi>Y<\/mml:mi><\/mml:mrow><\/mml:math>), and the anterior-posterior (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mrow><mml:mi>A<\/mml:mi><\/mml:mrow><\/mml:math>) and the transverse diameter (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mrow><mml:mi>B<\/mml:mi><\/mml:mrow><\/mml:math>) of spinal cord cross sections were measured at different cervical spinal segments (C4 to T1).<jats:italic>Results.<\/jats:italic>In cervical flexion position, a significant increase in<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mi>X<\/mml:mi><mml:mo>\/<\/mml:mo><mml:mi>Y<\/mml:mi><\/mml:math>of C4-5 segments was found in groups 2\u20135, the C5-6 and C6-7 segments in groups 1\u20135, and the C7-T1 segments in group 5 (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.05<\/mml:mn><\/mml:math>). The degree of the increased<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mi>X<\/mml:mi><mml:mo>\/<\/mml:mo><mml:mi>Y<\/mml:mi><\/mml:math>and cervical flexion<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\"><mml:mi>X<\/mml:mi><mml:mo>\/<\/mml:mo><mml:mi>Y<\/mml:mi><\/mml:math>of C5-6 segments were different among the 5 groups (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M9\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.05<\/mml:mn><\/mml:math>), which was likely due to rapid increases in<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M10\"><mml:mi>X<\/mml:mi><mml:mo>\/<\/mml:mo><mml:mi>Y<\/mml:mi><\/mml:math>during the course of Hirayama\u2019s disease.<jats:italic>Conclusion.<\/jats:italic>The<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M11\"><mml:mi>X<\/mml:mi><mml:mo>\/<\/mml:mo><mml:mi>Y<\/mml:mi><\/mml:math>change progression indicates that Hirayama disease may not be self-limiting.<\/jats:p>","DOI":"10.1155\/2015\/803148","type":"journal-article","created":{"date-parts":[[2015,10,19]],"date-time":"2015-10-19T21:07:09Z","timestamp":1445288829000},"page":"1-9","source":"Crossref","is-referenced-by-count":13,"title":["The Quantitative Assessment of Imaging Features for the Study of Hirayama Disease Progression"],"prefix":"10.1155","volume":"2015","author":[{"given":"Minghao","family":"Shao","sequence":"first","affiliation":[{"name":"Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai 200040, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Yin","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai 200040, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feizhou","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai 200040, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaojun","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai 200040, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongli","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai 200040, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianyuan","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Huashan Hospital, Fudan University, Shanghai 200040, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"issue":"2","key":"1","first-page":"2190","volume":"61","year":"1959","journal-title":"Folia Psychiatrica et Neurologica Japonica"},{"issue":"2","key":"2","first-page":"85","volume":"22","year":"1985","journal-title":"Shinkei Naika"},{"issue":"1","key":"3","first-page":"17","volume":"60","year":"2008","journal-title":"Brain and Nerve"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/s0090-3019(97)00451-5"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20980"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1097\/CND.0b013e3182461afc"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-010-0405-3"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-012-6674-4"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-008-1058-3"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1080\/14660820500396877"},{"issue":"2","key":"11","first-page":"365","volume":"19","year":"1998","journal-title":"American Journal of Neuroradiology"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000120665.81001.40"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2010.07.021"},{"issue":"6","key":"14","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1177\/0883073812442591","volume":"27","year":"2012","journal-title":"Journal of Child Neurology"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/0924-980x(94)00246-4"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/803148.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/803148.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/803148.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,23]],"date-time":"2017-06-23T21:35:57Z","timestamp":1498253757000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/bmri\/2015\/803148\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":15,"alternative-id":["803148","803148"],"URL":"https:\/\/doi.org\/10.1155\/2015\/803148","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}