{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:48:43Z","timestamp":1787017723147,"version":"build-2736575974"},"reference-count":14,"publisher":"Wiley","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100004160","name":"Mazandaran University of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004160","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>\n                    The aim of this study was to assess the candidal colonization and specific humoral responses against\n                    <jats:italic>Candida albicans<\/jats:italic>\n                    in patients with atopic dermatitis. One hundred patients with atopic dermatitis and 50 healthy individuals were enrolled in the study. Skin and oral specimens from all participants were cultured on CHROMagar\n                    <jats:italic>Candida<\/jats:italic>\n                    medium. Isolated yeasts were identified by using the sequence of the D1\/D2 domain of the 26S rRNA gene. ELISA was used for detection of IgM, IgA, and IgG antibodies against\n                    <jats:italic>C. albicans<\/jats:italic>\n                    in sera of participants.\n                    <jats:italic>Candida<\/jats:italic>\n                    species were isolated from the skin and oral cavity of 31% of the patients and 12% of the controls. There was no significant difference between\n                    <jats:italic>Candida<\/jats:italic>\n                    colonization in patients and controls (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\">\n                      <mml:mrow>\n                        <mml:mi>P&gt;0.05<\/mml:mi>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ).\n                    <jats:italic>Candida albicans<\/jats:italic>\n                    was isolated from the skin and oral cavity of 23% of the patients and 6% of the controls (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\">\n                      <mml:mrow>\n                        <mml:mi>P&lt; 0.05<\/mml:mi>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ). There were no significant differences between serum levels of IgM and IgA in patients and controls (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\">\n                      <mml:mrow>\n                        <mml:mi>P&gt;0.05<\/mml:mi>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ). Serum level of IgG was significantly lower in patients than in controls (\n                    <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\">\n                      <mml:mrow>\n                        <mml:mi>P&lt;0.05<\/mml:mi>\n                      <\/mml:mrow>\n                    <\/mml:math>\n                    ). Type of\n                    <jats:italic>Candida<\/jats:italic>\n                    colonization can change in patients with atopic dermatitis. In addition, these patients have abnormalities in the production of antibodies against\n                    <jats:italic>Candida albicans<\/jats:italic>\n                    that may have a role in the pathogenesis of atopic dermatitis.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:ext-link ext-link-type=\"Corrigendum\"\/>\n                    <jats:bold>\n                      Corrigendum to \u201cEvaluation of\n                      <jats:italic>Candida<\/jats:italic>\n                      Colonization and Specific Humoral Responses against\n                      <jats:italic>Candida albicans<\/jats:italic>\n                      in Patients with Atopic Dermatitis\u201d\n                    <\/jats:bold>\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"dx.doi.org\/10.1155\/2015\/142453\"\/>\n                  <\/jats:p>","DOI":"10.1155\/2015\/849206","type":"journal-article","created":{"date-parts":[[2015,4,8]],"date-time":"2015-04-08T11:09:18Z","timestamp":1428491358000},"page":"1-5","source":"Crossref","is-referenced-by-count":36,"title":["Evaluation of\n                    <i>Candida<\/i>\n                    Colonization and Specific Humoral Responses against\n                    <i>Candida albicans<\/i>\n                    in Patients with Atopic Dermatitis"],"prefix":"10.1155","volume":"2015","author":[{"given":"Ghaffari","family":"Javad","sequence":"first","affiliation":[{"name":"Department of Pediatrics, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Taheri Sarvtin","sequence":"additional","affiliation":[{"name":"Department of Medical Mycology and Parasitology, School of Medicine, Jiroft University of Medical Sciences, Jiroft, Iran"},{"name":"Department of Medical Mycology 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