{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T02:38:14Z","timestamp":1784169494387,"version":"3.55.0"},"reference-count":21,"publisher":"Wiley","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81173232"],"award-info":[{"award-number":["81173232"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2015]]},"abstract":"To assess the clinical effects and safety of Huangqi Jianzhong Tang (HQJZ) for the treatment of chronic gastritis (CG), three English databases and four Chinese databases were searched through the inception to January 2015. In randomized controlled trials (RCTs) comparing HQJZ with placebo, no intervention and western medicine were included. A total of 9 RCTs involving 979 participants were identified. The methodological quality of the included trials was generally poor. Meta-analyses demonstrated that HQJZ plus conventional medicine was more effective in improving overall gastroscopy outcome than western medicine alone for treatment of chronic superficial gastritis with the pooling result of overall improvement [OR 3.78 (1.29,11.06<\/mml:mn><\/mml:mrow><\/mml:math>),P<\/mml:mi>=<\/mml:mo>0.02<\/mml:mn><\/mml:math>]. In addition, the combination of HQJZ with antibiotics has higher overall effect rate than antibiotics alone for the treatment of CG [OR 2.60 (1.49,4.54<\/mml:mn><\/mml:mrow><\/mml:math>),P<\/mml:mi>=<\/mml:mo>0.0007<\/mml:mn><\/mml:math>]. There were no serious adverse events reported in both the intervention and controlled groups. HQJZ has the potential of improvement of the patients\u2019 gastroscopy outcomes,Helicobacter pylori<\/jats:italic>clearance rate, traditional Chinese Medicine syndromes, and overall effect rate alone or in combination use with conventional western medicine for chronic atrophic gastritis. However, due to poor methodological quality, the beneficial effect and safeties of HQJZ for CG could not be confirmed.<\/jats:p>","DOI":"10.1155\/2015\/878164","type":"journal-article","created":{"date-parts":[[2015,12,27]],"date-time":"2015-12-27T21:03:53Z","timestamp":1451250233000},"page":"1-11","source":"Crossref","is-referenced-by-count":40,"title":["Huangqi Jianzhong Tang for Treatment of Chronic Gastritis: A Systematic Review of Randomized Clinical Trials"],"prefix":"10.1155","volume":"2015","author":[{"given":"Yue","family":"Wei","sequence":"first","affiliation":[{"name":"The Third Affiliated Hospital of Beijing University of Chinese Medicine, 51 An Wai Xiaoguan Street, Chaoyang District, Beijing 100029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Xin","family":"Ma","sequence":"additional","affiliation":[{"name":"Hebei University, Baoding, Hebei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng-Jun","family":"Yin","sequence":"additional","affiliation":[{"name":"The Second Hospital of Tianjin Medical University, Tianjin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"An","sequence":"additional","affiliation":[{"name":"The Third Affiliated Hospital of Beijing University of Chinese Medicine, 51 An Wai Xiaoguan Street, Chaoyang District, Beijing 100029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Wei","sequence":"additional","affiliation":[{"name":"General Forestry Station of Beijing Municipality, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin-Xiang","family":"Yang","sequence":"additional","affiliation":[{"name":"The Third Affiliated Hospital of Beijing University of Chinese Medicine, 51 An Wai Xiaoguan Street, Chaoyang District, Beijing 100029, 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