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The primary outcomes included dyspeptic symptoms, quality of life, and mental status. The secondary outcomes included the fasting serum gastrin concentration, and frequency and propagation velocity of gastric slow waves. Sixty patients with FD were included, among whom, four dropped out. After one month's treatment, patients with FD showed significant improvements in primary (in both groups) and secondary (in the eight patients of the treatment group) outcomes as compared with baseline (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.0078<\/mml:mn><\/mml:math>to &lt;0.0001); treatment group has better outcomes in all primary outcome measures (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.0001<\/mml:mn><\/mml:math>except for SDS (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.0005<\/mml:mn><\/mml:math>)). Improvements on dyspeptic symptoms persist during follow-up (better in the treatment group). Acupuncture with manual manipulation had better effects on improving dyspeptic symptoms, mental status, and quality of life in patients with FD. These effects may be related to the increased frequency and propagation speed of gastric slow waves and serum gastrin secretion.<\/jats:p>","DOI":"10.1155\/2015\/904926","type":"journal-article","created":{"date-parts":[[2015,7,30]],"date-time":"2015-07-30T17:32:07Z","timestamp":1438277527000},"page":"1-9","source":"Crossref","is-referenced-by-count":25,"title":["Acupuncture for Functional Dyspepsia: A Single Blinded, Randomized, Controlled Trial"],"prefix":"10.1155","volume":"2015","author":[{"given":"Yulian","family":"Jin","sequence":"first","affiliation":[{"name":"Department of Acupuncture and Moxibustion, Guang An Men Hospital, China Academy of Chinese Medical Sciences, No. 5 Beixiange Street, Xicheng District, Beijing 100053, China"},{"name":"Department of Radiology, Guang An Men Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, 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