{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T21:03:29Z","timestamp":1790283809075,"version":"4.1.0"},"reference-count":28,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p><jats:italic>Purpose<\/jats:italic>. To assess and compare the anterior and posterior corneal surface parameters, keratoconus indices, thickness profile data, and data from enhanced elevation maps of keratoconic and normal corneas with the Pentacam Scheimpflug corneal tomography and to determine the sensitivity and specificity of these parameters in discriminating keratoconus from normal eyes.<jats:italic>Methods<\/jats:italic>. The study included 656 keratoconus eyes and 515 healthy eyes with a mean age of<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mn>30.95<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>9.25<\/mml:mn><\/mml:math>and<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mn>32.90<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>14.78<\/mml:mn><\/mml:math>years, respectively. Forty parameters obtained from the Pentacam tomography were assessed by the receiver operating characteristic curve analysis for their efficiency.<jats:italic>Results<\/jats:italic>. Receiver operating characteristic curve analyses showed excellent predictive accuracy (area under the curve, ranging from 0.914 to 0.972) for 21 of the 40 parameters evaluated. Among all parameters indices of vertical asymmetry, keratoconus index, front elevation at thinnest location, back elevation at thinnest location, Ambr\u00f3sio Relational Thickness (ARTmax), deviation of average pachymetric progression, deviation of ARTmax, and total deviation showed excellent (&gt;90%) sensitivity and specificity in addition to excellent area under the receiver operating characteristic curve (AUROC).<jats:italic>Conclusions<\/jats:italic>. Parameters derived from the topometric and Belin-Ambr\u00f3sio enhanced ectasia display maps very effectively discriminate keratoconus from normal corneas with excellent sensitivity and specificity.<\/jats:p>","DOI":"10.1155\/2015\/925414","type":"journal-article","created":{"date-parts":[[2015,3,24]],"date-time":"2015-03-24T23:33:19Z","timestamp":1427239999000},"page":"1-8","source":"Crossref","is-referenced-by-count":39,"title":["Comparative Analysis of Anterior Segment Parameters in Normal and Keratoconus Eyes Generated by Scheimpflug Tomography"],"prefix":"10.1155","volume":"2015","author":[{"given":"Faik","family":"Orucoglu","sequence":"first","affiliation":[{"name":"Birinci Eye Hospital, 34520 Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebru","family":"Toker","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, School of Medicine, Marmara University, 34782 Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6257(97)00119-7"},{"issue":"5","key":"2","doi-asserted-by":"crossref","first-page":"371","DOI":"10.3928\/1081-597X-19950901-14","volume":"11","year":"1995","journal-title":"Journal of Refractive Surgery"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2003.033670"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2007.12.036"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e31819e34de"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2006.06.025"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2013.03.023"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(92)90192-P"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1097\/ico.0b013e31818c4d62"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2008.07.006"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1097\/opx.0b013e3181f321aa"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e3180de1e04"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e3181861c29"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2009.11.012"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1097\/opx.0000000000000295"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2010.12.049"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2013.07.007"},{"key":"18","year":"2001"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0420.2002.800406.x"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S44741"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.4103\/0301-4738.116059"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2006.02.060"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1097\/ico.0b013e31819e34de"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2013-304132"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2008.02.020"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2013.03.023"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2006.06.025"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.3928\/1081597X-20110721-01"}],"container-title":["Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2015\/925414.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2015\/925414.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2015\/925414.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,31]],"date-time":"2020-08-31T04:28:45Z","timestamp":1598848125000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/joph\/2015\/925414\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":28,"alternative-id":["925414","925414"],"URL":"https:\/\/doi.org\/10.1155\/2015\/925414","relation":{},"ISSN":["2090-004X","2090-0058"],"issn-type":[{"value":"2090-004X","type":"print"},{"value":"2090-0058","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}