{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T19:03:05Z","timestamp":1740164585640,"version":"3.37.3"},"reference-count":61,"publisher":"Wiley","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Oncological Medicine"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>An inflammatory myofibroblastic tumor (IMT) is an immunohistochemically diverse entity demonstrating neoplastic and nonneoplastic qualities. Although IMTs can arise in any area of the body, lesions arising in certain sites, namely, the nasal cavity, paranasal sinuses, and pterygopalatine fossa, demonstrate a heightened neoplastic and invasive potential. Despite case specific complete tumor regression and disease remission in response to pharmacotherapeutics, a subset of IMTs remain resistant to all forms of therapy. We present such a case, a 34-year-old female patient, with a highly resistant, maxillary sinus IMT. Her refractory, ALK-1 negative IMT has not responded well to novel therapies reported in current literature. This case suggests the role of zonal expressivity within a single lesion as a probable mechanism for its highly resistant nature and should promote determination of each IMT\u2019s cytogenetic profile to provide more effective targeted therapy. Paper includes a literature review of all maxillary sinus IMTs from 1985 to 2014 along with their immunohistochemical staining, treatments, and outcomes.<\/jats:p>","DOI":"10.1155\/2015\/953857","type":"journal-article","created":{"date-parts":[[2015,2,11]],"date-time":"2015-02-11T21:12:34Z","timestamp":1423689154000},"page":"1-9","source":"Crossref","is-referenced-by-count":5,"title":["Maxillary Sinus Inflammatory Myofibroblastic Tumors: A Review and Case Report"],"prefix":"10.1155","volume":"2015","author":[{"given":"Chase C.","family":"Hansen","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colby","family":"Eisenbach","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Torres","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne","family":"Graham","sequence":"additional","affiliation":[{"name":"Department of Pathology, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0162-7350","authenticated-orcid":true,"given":"Fred","family":"Hardwicke","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","first-page":"119","volume":"9","year":"1939","journal-title":"The Journal of Thoracic and Cardiovascular Surgery"},{"key":"2","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0096-5588(20)30758-3","volume":"28","year":"1954","journal-title":"The Journal of Thoracic Surgery"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199508000-00001"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.4103\/0976-237x.91787"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.56.9.715"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.49.2.164"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1258\/0022215011908234"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20196"},{"issue":"6","key":"34","first-page":"1133","volume":"20","year":"1999","journal-title":"American Journal of Neuroradiology"},{"issue":"3","key":"35","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1177\/014556131409300308","volume":"93","year":"2014","journal-title":"Ear, Nose & Throat Journal"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.4103\/0973-029x.119754"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1016\/j.crad.2012.08.002"},{"issue":"3","key":"22","first-page":"E60","volume":"52","year":"2009","journal-title":"Canadian Journal of Surgery"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2013.1260"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1007056"},{"issue":"4","key":"9","first-page":"364","volume":"11","year":"1998","journal-title":"Modern Pathology"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9440(10)64550-6"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3880352"},{"issue":"3","key":"12","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1002\/1096-9896(200011)192:3<277::AID-PATH749>3.0.CO;2-E","volume":"192","year":"2000","journal-title":"The Journal of Pathology"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.3780118"},{"issue":"5","key":"14","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1093\/ajcp\/94.5.538","volume":"94","year":"1990","journal-title":"The American Journal of Clinical Pathology"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1995.tb01521.x"},{"key":"20","first-page":"279","volume":"12","year":"1999","journal-title":"Modern Pathology"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19930915)72:6<2042::AID-CNCR2820720641>3.0.CO;2-I"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200111000-00003"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000213393.57322.c7"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19900401)65:7<1626::AID-CNCR2820650729>3.0.CO;2-V"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1007\/bf02456289"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199112000-00005"},{"issue":"11","key":"7","first-page":"1138","volume":"118","year":"1994","journal-title":"Archives of Pathology and Laboratory Medicine"},{"issue":"4","key":"26","first-page":"623","volume":"28","year":"2007","journal-title":"Saudi Medical Journal"},{"issue":"2","key":"28","first-page":"85","volume":"15","year":"1998","journal-title":"Seminars in Diagnostic Pathology"},{"issue":"4","key":"16","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1182\/blood.V74.4.1360.1360","volume":"74","year":"1989","journal-title":"Blood"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199505000-00011"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1067\/s0002-9378(03)00208-4"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/103646"},{"issue":"5","key":"39","doi-asserted-by":"crossref","first-page":"E1","DOI":"10.1177\/014556131209100513","volume":"91","year":"2012","journal-title":"Ear, Nose and Throat Journal"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215111001848"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2011.05.004"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.4103\/0973-029x.86718"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcped.2009.09.020"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1237709"},{"issue":"10","key":"45","first-page":"1597","volume":"117","year":"2004","journal-title":"Chinese Medical Journal"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1016\/s0385-8146(02)00024-x"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.1067\/mhn.2001.117165"},{"issue":"7","key":"48","first-page":"1394","volume":"22","year":"2001","journal-title":"American Journal of Neuroradiology"},{"issue":"3","key":"49","first-page":"518","volume":"22","year":"2001","journal-title":"The American Journal of Neuroradiology"},{"key":"50","doi-asserted-by":"publisher","DOI":"10.1177\/000348949510400415"},{"key":"51","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.163.3.8079869"},{"issue":"4","key":"52","first-page":"784","volume":"15","year":"1994","journal-title":"The American Journal of Neuroradiology"},{"issue":"4","key":"53","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1017\/S0022215100126775","volume":"108","year":"1994","journal-title":"The Journal of Laryngology & Otology"},{"issue":"6","key":"54","first-page":"569","volume":"34","year":"1993","journal-title":"Singapore Medical Journal"},{"issue":"4","key":"55","first-page":"233","volume":"28","year":"1993","journal-title":"Zhonghua Er Bi Yan Hou Ke Za Zhi"},{"key":"56","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2880140311"},{"issue":"4","key":"57","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1002\/1097-0142(19910215)67:4<929::AID-CNCR2820670412>3.0.CO;2-Q","volume":"67","year":"1991","journal-title":"Cancer"},{"issue":"5","key":"58","first-page":"351","volume":"41","year":"1990","journal-title":"Acta Otorrinolaringologica Espanola"},{"issue":"2","key":"59","first-page":"123","volume":"28","year":"1990","journal-title":"Rhinology"},{"issue":"6, part 1","key":"60","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1288\/00005537-198806000-00006","volume":"98","year":"1988","journal-title":"Laryngoscope"},{"issue":"5","key":"61","first-page":"560","volume":"96","year":"1986","journal-title":"Laryngoscope"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2007.04.047"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-005-1593-1"}],"container-title":["Case Reports in Oncological Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crionm\/2015\/953857.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crionm\/2015\/953857.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crionm\/2015\/953857.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T04:54:02Z","timestamp":1717736042000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crionm\/2015\/953857\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":61,"alternative-id":["953857","953857"],"URL":"https:\/\/doi.org\/10.1155\/2015\/953857","relation":{},"ISSN":["2090-6706","2090-6714"],"issn-type":[{"type":"print","value":"2090-6706"},{"type":"electronic","value":"2090-6714"}],"subject":[],"published":{"date-parts":[[2015]]}}}