{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T02:20:32Z","timestamp":1771467632194,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,6,11]],"date-time":"2015-06-11T00:00:00Z","timestamp":1433980800000},"content-version":"vor","delay-in-days":161,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Dentistry"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:p>Apexification is a process of forming a mineralized apical barrier and had been performed by using calcium hydroxide paste, due to its biological and healing performances in cases of existent trauma. This clinical report aims to report the results of a 16\u2010year follow\u2010up study of an apexification treatment applied to nonvital tooth 22 of a healthy 8\u2010year\u2010old male after a trauma. \nClinical inspection of the tooth showed fractures of the incisal edge and mesial angle, absence of coronal mobility, and negative pulp vitality under cold testing. Radiographic analysis of the root revealed incomplete apex formation. The possibility of fracture into the root or luxation injury was rejected, and the diagnosis of pulp necrosis was verified. Apexification by calcium hydroxide and subsequent endodontic treatment were planned. Initial formation of the mineralized apical barrier was observed after 3 months, and the barrier was considered to be completed after 8 months. Clinical, radiographic, and CBCT examinations after 16 years verified the success of the treatment, although the choice of calcium hydroxide for apexification treatment is discussed.<\/jats:p>","DOI":"10.1155\/2015\/984590","type":"journal-article","created":{"date-parts":[[2015,6,11]],"date-time":"2015-06-11T21:42:25Z","timestamp":1434058945000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Apexification of an Immature Permanent Incisor with the Use of Calcium Hydroxide: 16\u2010Year Follow\u2010Up of a Case"],"prefix":"10.1155","volume":"2015","author":[{"given":"Camila Maggi Maia","family":"Silveira","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C\u00e1tia Cilene Nass","family":"Sebr\u00e3o","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larissa Soares Reis","family":"Vilanova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfonso","family":"S\u00e1nchez-Ayala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,6,11]]},"reference":[{"key":"e_1_2_6_1_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2011.00984.x"},{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2011.01049.x"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2011.01886.x"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2011.01089.x"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1999.tb00787.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/0022034512459054"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2011.01103.x"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1966.0017"},{"key":"e_1_2_6_9_2","first-page":"29","article-title":"Radiographic appearance of apical closure in apexification: follow-up after 7\u201313 years","volume":"7","author":"Ballesio I.","year":"2006","journal-title":"European Journal of Paediatric Dentistry"},{"key":"e_1_2_6_10_2","first-page":"165","article-title":"Apexification with a new intra-canal medicament: a multidisciplinary case report","volume":"7","author":"Soares A. D. J.","year":"2012","journal-title":"Iranian Endodontic Journal"},{"key":"e_1_2_6_11_2","first-page":"69","article-title":"Literature survey of apexification in connection with three cases","volume":"97","author":"Tarj\u00e1n I.","year":"2004","journal-title":"Fogorvosi Szemle"},{"key":"e_1_2_6_12_2","first-page":"190","article-title":"Induced root apexification following traumatic injuries of the pulp in children: follow-up study","volume":"55","author":"Th\u00e4ter M.","year":"1988","journal-title":"ASDC Journal of Dentistry for Children"},{"key":"e_1_2_6_13_2","first-page":"38","article-title":"Apexification: follow-up after 6\u201312 years","volume":"8","author":"Chawla H. S.","year":"1991","journal-title":"Journal of Indian Society of Pedodontics & Preventive Dentistry"},{"key":"e_1_2_6_14_2","first-page":"41","article-title":"Apexification with mineral trioxide aggregate: an overview of the material and technique","volume":"15","author":"Gaitonde P.","year":"2007","journal-title":"The European journal of prosthodontics and restorative dentistry"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1992.tb00451.x"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004770-200202000-00011"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.don.0000140584.65320.cc"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1590\/S1678-77572003000400002"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2591.1999.00232.x"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2009.01627.x"}],"container-title":["Case Reports in Dentistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crid\/2015\/984590.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crid\/2015\/984590.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1155\/2015\/984590","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:48:44Z","timestamp":1762476524000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1155\/2015\/984590"}},"subtitle":[],"editor":[{"given":"Sonja","family":"Pezelj Ribari\u0107","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["10.1155\/2015\/984590"],"URL":"https:\/\/doi.org\/10.1155\/2015\/984590","archive":["Portico"],"relation":{},"ISSN":["2090-6447","2090-6455"],"issn-type":[{"value":"2090-6447","type":"print"},{"value":"2090-6455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1]]},"assertion":[{"value":"2015-02-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-05-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-06-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"984590"}}