{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T16:17:48Z","timestamp":1773677868064,"version":"3.50.1"},"reference-count":30,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Endocrinology"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. Nutritional deficiencies are common after bariatric surgery. We aimed to assess the prevalence and possible predictors of secondary hyperparathyroidism (SHPT) in bariatric patients.<jats:italic>Methods<\/jats:italic>. A total of 95 patients who had undergone Roux-en-Y gastric bypass (RYGB) or sleeve gastrectomy (SG) were assessed after a median of 3 years after surgery. Anthropometric\/demographic and weight-loss parameters were compared according to the presence of SHPT, independently for men\/premenopausal women and postmenopausal women.<jats:italic>Results<\/jats:italic>. SHPT was highly prevalent (men\/premenopausal women, 52.1%; postmenopausal women, 31.9%). Among men\/premenopausal women, multivariate analysis indicated that SHPT was predicted by (a) 25-hydroxyvitamin D levels (Exp(<jats:italic>B<\/jats:italic>) = 0.869,<jats:italic>P<\/jats:italic>-value = 0.037), independently of age, sex, smoking; (b) calcium (Exp(<jats:italic>B<\/jats:italic>) = 0.159,<jats:italic>P<\/jats:italic>-value = 0.033) and smoking, independently of age and sex; (c) magnesium (Exp(<jats:italic>B<\/jats:italic>) = 0.026,<jats:italic>P<\/jats:italic>-value = 0.046) and smoking, independently of age and sex. Among postmenopausal women, SHPT was predicted by menopausal age independently of age, smoking, and levels of 25-hydroxyvitamin D or calcium. The development of SHPT was not associated with the type of surgery.<jats:italic>Conclusions<\/jats:italic>. RYGB and SG exhibited similar effects regarding the regulation of the hypothalamus-pituitary-parathyroid axis after surgery. Vitamin D status and menopausal age appear to determine SHPT on the long term. SHPT should be sought and vigorously treated with calcium and vitamin D supplementation.<\/jats:p>","DOI":"10.1155\/2015\/984935","type":"journal-article","created":{"date-parts":[[2015,4,9]],"date-time":"2015-04-09T21:02:46Z","timestamp":1428613366000},"page":"1-7","source":"Crossref","is-referenced-by-count":20,"title":["Determinants of Secondary Hyperparathyroidism in Bariatric Patients after Roux-en-Y Gastric Bypass or Sleeve Gastrectomy: A Pilot Study"],"prefix":"10.1155","volume":"2015","author":[{"given":"Andreas","family":"Alexandrou","sequence":"first","affiliation":[{"name":"1st Department of Surgery, Laiko Athens General Hospital, University of Athens, 17 Agiou Thoma Street, 11527 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evangelia","family":"Tsoka","sequence":"additional","affiliation":[{"name":"2nd Department of Obstetrics and Gynecology, Aretaieio Hospital, University of Athens, 76 Vas. Sofias Avenue, 11528 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eleni","family":"Armeni","sequence":"additional","affiliation":[{"name":"2nd Department of Obstetrics and Gynecology, Aretaieio Hospital, University of Athens, 76 Vas. Sofias Avenue, 11528 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Demetrios","family":"Rizos","sequence":"additional","affiliation":[{"name":"Hormonal Laboratory, Aretaieio Hospital, University of Athens, 76 Vas. Sofias Avenue, 11528 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theodoros","family":"Diamantis","sequence":"additional","affiliation":[{"name":"1st Department of Surgery, Laiko Athens General Hospital, University of Athens, 17 Agiou Thoma Street, 11527 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Areti","family":"Augoulea","sequence":"additional","affiliation":[{"name":"2nd Department of Obstetrics and Gynecology, Aretaieio Hospital, University of Athens, 76 Vas. Sofias Avenue, 11528 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Constantinos","family":"Panoulis","sequence":"additional","affiliation":[{"name":"2nd Department of Obstetrics and Gynecology, Aretaieio Hospital, University of Athens, 76 Vas. 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