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In this paper, the mobile eHealth solution for remote patient monitoring during clinical trials is presented, together with the outcomes of quantitative and qualitative performance evaluation. The evaluation is a third step to improve the quality of the application after earlier Good Clinical Practice certification and validation with the participation of 10 patients and 3 general practitioners. This time the focus was on the usability which was evaluated by the seventeen participants divided into three age groups (18\u201328, 29\u201350, and 50+). 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