{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T17:45:37Z","timestamp":1740159937779,"version":"3.37.3"},"reference-count":23,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pregnancy"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. To investigate whether the perinatal risks associated with early vanishing twin (VT) syndrome differ between cleavage- or blastocyst-stage embryo transfers (ET) in fresh in vitro fertilization (IVF) cycles.<jats:italic>Methods<\/jats:italic>. Retrospective, single-center, cohort study of IVF cycles with fresh cleavage- or blastocyst-stage ETs resulting in a live singleton birth. The incidence of preterm birth (PTB), low birth weight (LBW), and very low birth weight (VLBW) was compared between cleavage- and blastocyst-stage ET cycles complicated by early VT.<jats:italic>Results<\/jats:italic>. 7241 patients had live singleton births. Early VT was observed in 709\/6134 (11.6%) and 70\/1107 (6.32%) patients undergoing cleavage-stage and blastocyst-stage ETs, respectively. Patients in the blastocyst-stage group were younger compared to the cleavage-stage group. The cleavage-stage group had a similar birth weight compared to the blastocyst-stage group. There was no difference in the incidence of PTB (9.87% versus 8.57%), LBW (11.1% versus 11.4%), or VLBW (1.13 versus 1.43%) when comparing the cleavage-stage early VT and blastocyst-stage early VT groups, even after adjustment with logistic regression.<jats:italic>Conclusions<\/jats:italic>. Our study highlights that the adverse perinatal risks of PTB, LBW, and VLBW associated with early VT syndrome are similar in patients undergoing cleavage-stage or blastocyst-stage ETs during fresh IVF cycles.<\/jats:p>","DOI":"10.1155\/2016\/1245210","type":"journal-article","created":{"date-parts":[[2016,12,22]],"date-time":"2016-12-22T16:20:24Z","timestamp":1482423624000},"page":"1-6","source":"Crossref","is-referenced-by-count":7,"title":["Perinatal Risks Associated with Early Vanishing Twin Syndrome following Transfer of Cleavage- or Blastocyst-Stage Embryos"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8160-5869","authenticated-orcid":true,"given":"Nigel","family":"Pereira","sequence":"first","affiliation":[{"name":"The Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine P.","family":"Pryor","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Weill Cornell Medical College, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allison C.","family":"Petrini","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Weill Cornell Medical College, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jovana P.","family":"Lekovich","sequence":"additional","affiliation":[{"name":"The Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaclyn","family":"Stahl","sequence":"additional","affiliation":[{"name":"The Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rony T.","family":"Elias","sequence":"additional","affiliation":[{"name":"The Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven D.","family":"Spandorfer","sequence":"additional","affiliation":[{"name":"The Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medicine, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"issue":"7","key":"1","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1093\/humrep\/dew082","volume":"31","year":"2016","journal-title":"Human Reproduction"},{"volume":"7","journal-title":"Cochrane Database of Systematic Reviews","year":"2012","key":"2"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2016.06.029"},{"issue":"11","key":"4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15585\/mmwr.ss6411a1","volume":"64","year":"2015","journal-title":"MMWR Surveillance Summaries"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dei142"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2005.11.073"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.02.058"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2015.02.009"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.07.020"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.12968\/hmed.2006.67.8.21976"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dem225"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2009.11.015"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2007.06.048"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2011.12.032"},{"issue":"4","key":"15","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1177\/1745505716658898","volume":"12","year":"2016","journal-title":"Women's Health"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-0659-8_8"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0113671"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-0659-8_16"},{"first-page":"378","volume-title":"In vitro culture of human blastocysts","year":"1999","key":"19"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-015-0434-1"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1097\/aog.0b013e3182255999"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(95)00386-x"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(73)90609-1"}],"container-title":["Journal of Pregnancy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/jp\/2016\/1245210.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jp\/2016\/1245210.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jp\/2016\/1245210.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,25]],"date-time":"2017-06-25T02:33:29Z","timestamp":1498358009000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/jp\/2016\/1245210\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":23,"alternative-id":["1245210","1245210"],"URL":"https:\/\/doi.org\/10.1155\/2016\/1245210","relation":{},"ISSN":["2090-2727","2090-2735"],"issn-type":[{"type":"print","value":"2090-2727"},{"type":"electronic","value":"2090-2735"}],"subject":[],"published":{"date-parts":[[2016]]}}}