{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,9,21]],"date-time":"2022-09-21T12:21:41Z","timestamp":1663762901498},"reference-count":23,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Disease Markers"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>This study aimed to evaluate the association between serum galectin levels and renal dysfunction in relation to in-hospital prognosis and unfavorable prognosis 1 year after ST-elevated myocardial infarction (STEMI). Patients were assigned to two groups according to the cystatin C-based estimate of GFR on day 12 after STEMI: (1) STEMI patients with normal renal function (GFR based on cystatin C levels = 60\u2009mL\/min\/1.73\u2009m<jats:sup>2<\/jats:sup>) and (2) those with renal dysfunction (RD) (GFR based on cystatin C levels &lt;60\u2009mL\/min\/1.73\u2009m<jats:sup>2<\/jats:sup>). A decrease in GFR estimated from the CKD-EPI equation on day 12 was more frequently found in patients with a reduced GFR based on cystatin C levels (41.9%) compared with those without RD (21.3%). Galectin levels exceeded the cut-off value (17.8\u2009ng\/mL) in 50.6% of cases in the group with GFR &lt;60\u2009mL\/min\/1.73\u2009m<jats:sup>2<\/jats:sup>and in 32% of cases in the group with a normal GFR. The presence of RD and elevated galectin levels &gt;17.8\u2009ng\/mL on day 12 after MI are independent predictors of an adverse prognosis at 1 year in STEMI patients. Elevated galectin levels are directly correlated with the presence of early postinfarction angina.<\/jats:p>","DOI":"10.1155\/2016\/1549063","type":"journal-article","created":{"date-parts":[[2016,2,15]],"date-time":"2016-02-15T16:00:35Z","timestamp":1455552035000},"page":"1-6","source":"Crossref","is-referenced-by-count":2,"title":["Serum Galectin and Renal Dysfunction in ST-Segment Elevation Myocardial Infarction"],"prefix":"10.1155","volume":"2016","author":[{"given":"Victoria","family":"Karetnikova","sequence":"first","affiliation":[{"name":"Federal State Budgetary Institution \u201cResearch Institute for Complex Issues of Cardiovascular Diseases\u201d, 6 Sosnovy Boulevard, Kemerovo 650002, Russia"},{"name":"Federal State Budget Educational Institution of Higher Professional Education \u201cKemerovo State Medical Academy of the Ministry of Health of the Russian Federation\u201d, 22a Voroshilov Street, Kemerovo 650029, 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