{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,20]],"date-time":"2025-07-20T03:32:59Z","timestamp":1752982379908},"reference-count":9,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Hematology"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>Thrombotic thrombocytopenic purpura (TTP) is a life-threatening disorder involving thrombotic microangiopathy and is characterized by increased platelet aggregation throughout the body. Acquired TTP can be triggered by a variety of conditions including infections. We hereby describe a case report of an 81-year-old female presenting to the internal medicine department with TTP and active chronic gastritis, positive for<jats:italic>Helicobacter pylori<\/jats:italic>(<jats:italic>H. pylori<\/jats:italic>) on biopsy. The TTP was highly resistant to medical therapy; however the patient underwent complete resolution of her TTP following<jats:italic>H. pylori<\/jats:italic>eradication. We conclude that acquired TTP may be triggered by<jats:italic>H. pylori<\/jats:italic>infection and that treating the underlying infection may play a role in improving TTP\u2019s outcome in some patients, especially when disease is refractory to medical therapy.<\/jats:p>","DOI":"10.1155\/2016\/1568586","type":"journal-article","created":{"date-parts":[[2016,4,5]],"date-time":"2016-04-05T21:00:45Z","timestamp":1459890045000},"page":"1-3","source":"Crossref","is-referenced-by-count":2,"title":["Marked Improvement in Refractory TTP Directly after<i>H. pylori<\/i>Eradication Therapy"],"prefix":"10.1155","volume":"2016","author":[{"given":"Irina","family":"Gringauz","sequence":"first","affiliation":[{"name":"Internal Medicine Ward T, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Narin Nard","family":"Carmel-Neiderman","sequence":"additional","affiliation":[{"name":"Hasharon Hospital, Campus Rabin, Petah Tikva, Israel"},{"name":"Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tobin","family":"Mangel","sequence":"additional","affiliation":[{"name":"St George\u2019s University of London, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orith","family":"Portnoy","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Imaging, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gad","family":"Segal","sequence":"additional","affiliation":[{"name":"Internal Medicine Ward T, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Idan","family":"Goren","sequence":"additional","affiliation":[{"name":"Internal Medicine Ward T, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"1","first-page":"21","volume":"24","year":"1924","journal-title":"Proceedings of the New York Pathological Society"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2005.01436.x"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1111\/trf.12263"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(05)71144-2"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(90)90470-x"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1056\/nejmcp053024"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-07-271445"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2005.06.015"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0012.2004.00224.x"}],"container-title":["Case Reports in Hematology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2016\/1568586.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2016\/1568586.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2016\/1568586.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,18]],"date-time":"2016-08-18T13:20:03Z","timestamp":1471526403000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crihem\/2016\/1568586\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":9,"alternative-id":["1568586","1568586"],"URL":"https:\/\/doi.org\/10.1155\/2016\/1568586","relation":{},"ISSN":["2090-6560","2090-6579"],"issn-type":[{"value":"2090-6560","type":"print"},{"value":"2090-6579","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}