{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T09:10:30Z","timestamp":1759482630624,"version":"3.37.3"},"reference-count":8,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Canadian Respiratory Journal"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p><jats:italic>Background.<\/jats:italic> Lung cancer is the leading cause of malignancy related mortality in the United States. Accurate staging of NSCLC influences therapeutic decisions. Transbronchial needle aspiration (TBNA) and endobronchial ultrasound-guided TBNA (EBUS-TBNA) has been accepted as a procedure for the diagnosis and staging of lung cancer. The aim of this study is to evaluate the efficacy and adequacy of TBNA and EBUS-TBNA for sampling of mediastinal adenopathy using the Wang\u2019s eleven lymph node map stations.<jats:italic> Methods.<\/jats:italic> We retrospectively reviewed 99 consecutive cases diagnosed with malignancy by EBUS-TBNA and a series 74 patients evaluated for mediastinal adenopathy or a pulmonary lesion using conventional transbronchial needle aspiration. The IASLC lymph node map was correlated with Wang\u2019s map.<jats:italic> Results.<\/jats:italic> A total of 182 lymph node stations were sampled using EBUS-TBNA. 96 were positive for nodal metastasis. A total of four cases of samples taken from station 2R showed malignant cells. From the 74 cases series using cTBNA 167 nodes were sampled in 222 passes. Lymphoid or malignant tissue was obtained in 67 (91.8%) cases; 55.1% of the nodes were 1 cm or less.<jats:italic> Conclusions.<\/jats:italic> The use of the eleven stations described in Wang\u2019s map to guide TBNA of the mediastinal nodes allows sampling of radiologically considered nonpathological nodes. These data suggest that Wang\u2019s map covers the most frequent IASLC nodal stations compromised with metastasis.<\/jats:p>","DOI":"10.1155\/2016\/1652178","type":"journal-article","created":{"date-parts":[[2016,12,12]],"date-time":"2016-12-12T18:06:45Z","timestamp":1481566005000},"page":"1-4","source":"Crossref","is-referenced-by-count":5,"title":["Role of the Endobronchial Landmarks Guiding TBNA and EBUS-TBNA in Lung Cancer Staging"],"prefix":"10.1155","volume":"2016","author":[{"given":"S.","family":"Arias","sequence":"first","affiliation":[{"name":"Interventional Pulmonology, Division of Pulmonary Medicine and Critical Care, University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Q. H.","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Shandong Provincial Hospital Affiliated to Shandong University, 9677 Jingshi East Road, Jinan 250041, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Frimpong","sequence":"additional","affiliation":[{"name":"Interventional Pulmonology, Division of Pulmonary Medicine and Critical Care, Johns Hopkins University, School of Medicine, 1800 Orleans Street, Suite 7125L, Baltimore, MD 21287, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Lee","sequence":"additional","affiliation":[{"name":"Interventional Pulmonology, Division of Pulmonary Medicine and Critical Care, Johns Hopkins University, School of Medicine, 1800 Orleans Street, Suite 7125L, Baltimore, MD 21287, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Feller-Kopman","sequence":"additional","affiliation":[{"name":"Interventional Pulmonology, Division of Pulmonary Medicine and Critical Care, Johns Hopkins University, School of Medicine, 1800 Orleans Street, Suite 7125L, Baltimore, MD 21287, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.","family":"Yarmus","sequence":"additional","affiliation":[{"name":"Interventional Pulmonology, Division of Pulmonary Medicine and Critical Care, Johns Hopkins University, School of Medicine, 1800 Orleans Street, Suite 7125L, Baltimore, MD 21287, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0764-0791","authenticated-orcid":true,"given":"K. P.","family":"Wang","sequence":"additional","affiliation":[{"name":"Interventional Pulmonology, Division of Pulmonary Medicine and Critical Care, Johns Hopkins University, School of Medicine, 1800 Orleans Street, Suite 7125L, Baltimore, MD 21287, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"year":"2013","key":"1"},{"issue":"1","key":"2","first-page":"4","volume":"15","year":"2009","journal-title":"Annals of Thoracic and Cardiovascular Surgery"},{"issue":"8","key":"3","first-page":"588","volume":"37","year":"2014","journal-title":"Chinese Journal of Tuberculosis and Respiratory Diseases"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1097\/SGA.0b013e318214ea00"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1097\/lbr.0000000000000097"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2005.041525"},{"key":"7","first-page":"17","volume":"38","year":"1986","journal-title":"Japanese Journal of Nursing"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1590\/s1806-37132007000200006"}],"container-title":["Canadian Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crj\/2016\/1652178.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crj\/2016\/1652178.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crj\/2016\/1652178.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,12,26]],"date-time":"2016-12-26T16:01:34Z","timestamp":1482768094000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crj\/2016\/1652178\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":8,"alternative-id":["1652178","1652178"],"URL":"https:\/\/doi.org\/10.1155\/2016\/1652178","relation":{},"ISSN":["1198-2241","1916-7245"],"issn-type":[{"type":"print","value":"1198-2241"},{"type":"electronic","value":"1916-7245"}],"subject":[],"published":{"date-parts":[[2016]]}}}