{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T05:17:38Z","timestamp":1771478258941,"version":"3.50.1"},"reference-count":25,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Transplantation"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>The mortality in<jats:italic>Strongyloides<\/jats:italic>hyperinfection syndrome (SHS) is alarmingly high. This is particularly common in bone marrow, renal, and other solid organ transplant (SOT) patients, where figures may reach up to 50\u201385%. Immunosuppressives, principally corticosteroids, are the primary triggering factor. In general, the clinical features of<jats:italic>Strongyloides stercoralis<\/jats:italic>hyperinfection are nonspecific; therefore, a high index of suspicion is required for early diagnosis and starting appropriate therapy. Although recurrent Gram-negative sepsis and meningitis have been previously reported, the combination of both cytomegalovirus (CMV) and strongyloidiasis had rarely been associated. We here describe a patient who survived SHS with recurrent<jats:italic>Escherichia coli<\/jats:italic>(<jats:italic>E. coli<\/jats:italic>) urosepsis and CMV infection.<\/jats:p>","DOI":"10.1155\/2016\/1786265","type":"journal-article","created":{"date-parts":[[2016,9,15]],"date-time":"2016-09-15T17:06:15Z","timestamp":1473959175000},"page":"1-5","source":"Crossref","is-referenced-by-count":4,"title":["<i>Strongyloides<\/i>Hyperinfection Syndrome Combined with Cytomegalovirus Infection"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0465-3004","authenticated-orcid":true,"given":"Fatehi Elnour","family":"Elzein","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Prince Sultan Military Medical City, Riyadh 11159, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed","family":"Alsaeed","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Prince Sultan Military Medical City, Riyadh 11159, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sulafa","family":"Ballool","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Prince Sultan Military Medical City, Riyadh 11159, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashraf","family":"Attia","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Prince Sultan Military Medical City, Riyadh 11159, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0002214"},{"key":"2","first-page":"949","volume":"1","year":"1996","journal-title":"Clinical Infectious Diseases"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1179\/136485909X385009"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1086\/630201"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1007\/s11908-010-0150-z"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1056\/nejm196611172752003"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.4103\/1319-2442.148752"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1159\/000226298"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2007.03.047"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1128\/cmr.17.1.208-217.2004"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/153.1.178"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1111\/j.0141-9838.2004.00726.x"},{"issue":"2","key":"13","first-page":"128","volume":"66","year":"1999","journal-title":"The Mount Sinai Journal of Medicine"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.609"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2000.1.2.73"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.13-0494"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/16.12.2429"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-13-78"},{"issue":"14","key":"19","first-page":"264","volume":"62","year":"2013","journal-title":"MMWR Morbidity and Mortality Weekly Report"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/860976"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000075"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2015.04.001"},{"key":"23","volume":"1","year":"2016"},{"issue":"1","key":"24","doi-asserted-by":"crossref","first-page":"97","DOI":"10.4269\/ajtmh.2006.74.97","volume":"74","year":"2006","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD007745.pub3"}],"container-title":["Case Reports in Transplantation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crit\/2016\/1786265.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crit\/2016\/1786265.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crit\/2016\/1786265.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,13]],"date-time":"2019-09-13T11:15:03Z","timestamp":1568373303000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/crit\/2016\/1786265\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":25,"alternative-id":["1786265","1786265"],"URL":"https:\/\/doi.org\/10.1155\/2016\/1786265","relation":{},"ISSN":["2090-6943","2090-6951"],"issn-type":[{"value":"2090-6943","type":"print"},{"value":"2090-6951","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}