{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T15:09:35Z","timestamp":1746803375872,"version":"3.40.5"},"reference-count":13,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p><jats:italic>Introduction<\/jats:italic>. Four novices to Spectral Domain Optical Coherence Tomography (SD-OCT) image review were provided a brief lecture on the interpretation of iVue iWellnessExam<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mtext>\u2122<\/mml:mtext><\/mml:mrow><\/mml:math>findings (available on iVue<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mrow><mml:mi>\u00ae<\/mml:mi><\/mml:mrow><\/mml:math>SD-OCT, Optovue, Inc., Fremont, CA). For a cohort of 126 (Confirmed) Normal, 101 (Confirmed) Disease subjects, iWellnessExam<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mrow><mml:mtext>\u2122<\/mml:mtext><\/mml:mrow><\/mml:math>OD, OS, and OU reports were provided. Each novice independently reviewed and sorted the subjects into one of four categories: normal, retinal disease, optic nerve (ON) disease, and retinal + ON disease. Their accuracy is compared between the novices and with an expert reviewer.<jats:italic>Results<\/jats:italic>. Posterior segment disease was properly detected by novices with sensitivities of 90.6%, any disease; 84.3%, retinal disease; 88.0%, ON disease; expert sensitivity: 96.0%, 95.5%, and 90.0%, respectively; specificity: 84.3%, novices; 99.2%, expert. Novice accuracy correlates best with clinical exposure and amount of time spent reviewing each image set. The novices\u2019 negative predictive value was 92.0% (i.e., very few false negatives).<jats:italic>Conclusions<\/jats:italic>. Novices can be trained to screen for posterior segment disease efficiently and effectively using iWellnessExam<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mrow><mml:mtext>\u2122<\/mml:mtext><\/mml:mrow><\/mml:math>data, with high sensitivity, while maintaining high specificity. Novice reviewer accuracy covaries with both clinical exposure and time spent per image set. These findings support exploration of training nonophthalmic technicians in a primary medical care setting.<\/jats:p>","DOI":"10.1155\/2016\/1964254","type":"journal-article","created":{"date-parts":[[2016,1,6]],"date-time":"2016-01-06T16:03:31Z","timestamp":1452096211000},"page":"1-8","source":"Crossref","is-referenced-by-count":1,"title":["Novice Reviewers Retain High Sensitivity and Specificity of Posterior Segment Disease Identification with iWellnessExam<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mtext>\u2122<\/mml:mtext><\/mml:mrow><\/mml:math>"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7904-1547","authenticated-orcid":true,"given":"Samantha","family":"Slotnick","sequence":"first","affiliation":[{"name":"Private Practice, Scarsdale, NY 10583, USA"},{"name":"SUNY State College of Optometry, New York, NY 10036, USA"},{"name":"SUNY Eye Institute, Syracuse, NY 13202, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine","family":"Awad","sequence":"additional","affiliation":[{"name":"Nova Southeastern University College of Optometry, Fort Lauderdale, FL 33314, USA"},{"name":"University of Incarnate Word Rosenberg School of Optometry, San Antonio, TX 78229, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjeev","family":"Nath","sequence":"additional","affiliation":[{"name":"Eye Institute & Laser Center, New York, NY 10065, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerome","family":"Sherman","sequence":"additional","affiliation":[{"name":"SUNY State College of Optometry, New York, NY 10036, USA"},{"name":"SUNY Eye Institute, Syracuse, NY 13202, USA"},{"name":"Eye Institute & Laser Center, New York, NY 10065, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.2147\/eb.s40322"},{"volume":"50, article 3323","journal-title":"ARVO Meeting Abstracts","year":"2009","key":"2"},{"volume":"50, article 3326","journal-title":"ARVO Meeting Abstracts","year":"2009","key":"3"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2009.02015.x"},{"key":"6","first-page":"3324","volume":"50","year":"2009","journal-title":"Investigative Ophthalmology & Visual Science"},{"volume":"51, article 2742","journal-title":"ARVO Meeting Abstracts","year":"2010","key":"7"},{"key":"9","first-page":"216","volume":"51","year":"2010","journal-title":"Investigative Ophthalmology & Visual Science"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.09-5053"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1097\/ijg.0b013e31820d7e9d"},{"issue":"1","key":"12","doi-asserted-by":"crossref","first-page":"68","DOI":"10.2174\/1874364101509010068","volume":"9","year":"2015","journal-title":"The Open Ophthalmology Journal"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1111\/aos.12479"},{"issue":"4","key":"14","first-page":"496","volume":"26","year":"2014","journal-title":"Journal of Ayub Medical College Abbottabad"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.optm.2008.12.011"}],"container-title":["Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2016\/1964254.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2016\/1964254.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2016\/1964254.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,23]],"date-time":"2017-06-23T23:09:20Z","timestamp":1498259360000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/joph\/2016\/1964254\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":13,"alternative-id":["1964254","1964254"],"URL":"https:\/\/doi.org\/10.1155\/2016\/1964254","relation":{},"ISSN":["2090-004X","2090-0058"],"issn-type":[{"type":"print","value":"2090-004X"},{"type":"electronic","value":"2090-0058"}],"subject":[],"published":{"date-parts":[[2016]]}}}