{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T13:03:10Z","timestamp":1784120590063,"version":"3.55.0"},"reference-count":23,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p><jats:italic>Introduction<\/jats:italic>. Acute kidney injury (AKI) is a common occurrence in the intensive care unit (ICU). Studies have looked at outcomes of renal replacement therapy using intermittent haemodialysis (IHD) in ICUs with varying results. Little is known about the outcomes of using IHD in resource-limited settings where continuous renal replacement therapy (CRRT) is limited. We sought to determine outcomes of IHD among critically ill patients admitted to a low-income country ICU.<jats:italic>Methods<\/jats:italic>. A retrospective review of patient records was conducted. Patients admitted to the ICU who underwent IHD for AKI were included in the study. Patients\u2019 demographic and clinical characteristics, cause of AKI, laboratory parameters, haemodialysis characteristics, and survival were interpreted and analyzed. Primary outcome was mortality.<jats:italic>Results<\/jats:italic>. Of 62 patients, 40 had complete records. Median age of patients was 38.5 years. Etiologic diagnoses associated with AKI included sepsis, malaria, and ARDS. Mortality was 52.5%. APACHE II (OR 4.550; 95% CI 1.2\u201317.5,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.028<\/mml:mn><\/mml:math>), mechanical ventilation (OR 13.063; 95% CI 2.3\u201372,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.003<\/mml:mn><\/mml:math>), and need for vasopressors (OR 16.8; 95% CI 3.4\u201382.6,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">0.001<\/mml:mn><\/mml:math>) had statistically significant association with mortality.<jats:italic>Conclusion<\/jats:italic>. IHD may be a feasible alternative for RRT in critically ill haemodynamically stable patients in low resource settings where CRRT may not be available.<\/jats:p>","DOI":"10.1155\/2016\/2015251","type":"journal-article","created":{"date-parts":[[2016,3,3]],"date-time":"2016-03-03T21:03:03Z","timestamp":1457038983000},"page":"1-6","source":"Crossref","is-referenced-by-count":4,"title":["Clinical Characteristics and 30-Day Outcomes of Intermittent Hemodialysis for Acute Kidney Injury in an African Intensive Care Unit"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7025-0465","authenticated-orcid":true,"given":"Arthur","family":"Kwizera","sequence":"first","affiliation":[{"name":"Department of Anaesthesia, Makerere University, P.O. Box 7072, Kampala, Uganda"},{"name":"Dialysis and Intensive Care Unit, International Hospital Kampala, P.O. Box 8177, Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janat","family":"Tumukunde","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Makerere University, P.O. Box 7072, Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lameck","family":"Ssemogerere","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Makerere University, P.O. Box 7072, Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanuel","family":"Ayebale","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Makerere University, P.O. Box 7072, Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Agaba","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Makerere University, P.O. Box 7072, Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamali","family":"Yakubu","sequence":"additional","affiliation":[{"name":"Dialysis and Intensive Care Unit, International Hospital Kampala, P.O. Box 8177, Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aggrey","family":"Lubikire","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Makerere University, P.O. Box 7072, Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Nabukenya","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Makerere University, P.O. Box 7072, Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3211-163X","authenticated-orcid":true,"given":"Robert","family":"Kalyesubula","sequence":"additional","affiliation":[{"name":"Departments of Physiology and Internal Medicine Nephrology Unit, Makerere University, P.O. Box 7072, Kampala, Uganda"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.294.7.813"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1007\/s40620-014-0114-8"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9185.98357"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1378\/chest.07-0167"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-012-2706-x"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.4103\/0971-4065.107193"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2369-16-4"},{"key":"8","doi-asserted-by":"crossref","first-page":"S40","DOI":"10.1681\/ASN.V12suppl_1s40","volume":"12","year":"2001","journal-title":"Journal of the American Society of Nephrology"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-009-1588-z"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1007\/s10157-014-1028-4"},{"issue":"5","key":"11","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1177\/039139880402700506","volume":"27","year":"2004","journal-title":"International Journal of Artificial Organs"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfi296"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2014.411"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1159\/000334139"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1159\/0000102082"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1186\/1756-0500-5-475"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa0802639"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1186\/cc10252"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2007.12.017"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1186\/cc10061"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfq840"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2015.02.328"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1007\/s001340100953"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2016\/2015251.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2016\/2015251.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2016\/2015251.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,6]],"date-time":"2022-06-06T16:18:37Z","timestamp":1654532317000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/bmri\/2016\/2015251\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":23,"alternative-id":["2015251","2015251"],"URL":"https:\/\/doi.org\/10.1155\/2016\/2015251","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}