{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T11:27:05Z","timestamp":1787657225486,"version":"build-2736575974"},"reference-count":22,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pathogens"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>Urinary tract infections (UTIs) in pediatric population are associated with high morbidity and long term complications. In recent years, there is increased prevalence of<jats:italic>Escherichia coli<\/jats:italic>(<jats:italic>E. coli<\/jats:italic>) strains producing extended spectrum<jats:italic>\u03b2<\/jats:italic>-lactamase, Amp C, and Metallo<jats:italic>\u03b2<\/jats:italic>-lactamase, making the clinical management even more difficult. This study was aimed to detect the serotypes and to determine antimicrobial susceptibility profile of<jats:italic>E. coli<\/jats:italic>isolates from urine samples of children &lt;10 yrs old. A total of 75 pure<jats:italic>E. coli<\/jats:italic>strains isolated from patients with symptoms of UTI and colony count \u226510<jats:sup>5<\/jats:sup>organisms\/mL were included in the study. Antibiotic sensitivity pattern showed maximum resistance to nalidixic acid (98.7%), followed by ampicillin (97.3%), amoxi-clavulanate (96%), and fluoroquinolones (92%) while most of the isolates were found sensitive to piperacillin-tazobactam (13.3%), nitrofurantoin (5.3%), and meropenem (1.3%). 48% of the strains were ESBL producer (extended spectrum beta lactamase). 44% strains were typable withantisera used in our study and the most common serogroup was O6 (33.3%) followed by O1 (15.1%) and O15 (15.1%). To conclude, judicious use of antibiotics according to hospital antibiotic policy and infection control measures should be implemented to prevent spread of multidrug resistant organisms.<\/jats:p>","DOI":"10.1155\/2016\/2548517","type":"journal-article","created":{"date-parts":[[2016,3,7]],"date-time":"2016-03-07T16:00:59Z","timestamp":1457366459000},"page":"1-4","source":"Crossref","is-referenced-by-count":18,"title":["Serotyping and Antimicrobial Susceptibility Pattern of<i>Escherichia coli<\/i>Isolates from Urinary Tract Infections in Pediatric Population in a Tertiary Care Hospital"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8221-9177","authenticated-orcid":true,"given":"Shweta","family":"Sharma","sequence":"first","affiliation":[{"name":"Department of Microbiology, PGIMER and Dr. RML Hospital, New Delhi 110001, 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