{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T22:38:24Z","timestamp":1792276704067,"version":"4.4.0"},"reference-count":25,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p><jats:italic>Purpose.<\/jats:italic>Myomectomy has been performed through laparoscopy. Suturing is known as rate-limiting step in laparoscopic myomectomy. The present study was aimed at comparing the clinical outcomes of absorbable knotless wound closure device with the results of conventional suturing.<jats:italic>Methods<\/jats:italic>. This prospective study included 62 women who underwent laparoscopic myomectomy at Taipei City Hospital, Zhongxiao Branch, from January 2010 through to August 2012. The patients were randomized into two groups according to suturing materials, the knotless group and the 2-0 Vicryl suture group. Patient demographics, overall operative time, and intraoperative blood loss were compared between two groups.<jats:italic>Results<\/jats:italic>. Demographic characteristics and laboratory variables before surgery were comparable. Operative time was significantly shorter in knotless group compared with that in 2-0 Vicryl suture group (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mn fontstyle=\"italic\">112<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">47<\/mml:mn><\/mml:math>versus<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mn fontstyle=\"italic\">147<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">63<\/mml:mn><\/mml:math>minutes;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.05<\/mml:mn><\/mml:math>). The results revealed a significant difference in intraoperative blood loss between two groups (knotless versus 2-0 Vicryl:<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mn fontstyle=\"italic\">112.8<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">54.2<\/mml:mn><\/mml:math>versus<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mn fontstyle=\"italic\">143.6<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">64.9<\/mml:mn><\/mml:math>). Use of absorbable knotless wound closure device was associated with greater hemostasis compared with that of 2-0 Vicryl. During a 2-year follow-up period, 12 patients (46.2%) from the group with absorbable knotless wound closure device and 14 patients (38.9%) from 2-0 Vicryl suture group became pregnant.<jats:italic>Conclusion.<\/jats:italic>Closure of myometrium using absorbable knotless wound closure device after laparoscopic myomectomy resulted in a shorter operative time and less blood loss.<\/jats:p>","DOI":"10.1155\/2016\/2849476","type":"journal-article","created":{"date-parts":[[2016,6,27]],"date-time":"2016-06-27T19:14:10Z","timestamp":1467054850000},"page":"1-5","source":"Crossref","is-referenced-by-count":7,"title":["Feasibility and Safety of Absorbable Knotless Wound Closure Device in Laparoscopic Myomectomy"],"prefix":"10.1155","volume":"2016","author":[{"given":"Chying-Chyuan","family":"Chan","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Taipei City Hospital, Zhongxiao Branch, Taipei 11556, Taiwan"},{"name":"Department of Obstetrics and Gynecology, Taipei City Hospital, Renai Branch, Taipei 10629, Taiwan"},{"name":"National Defense Medical Center, Taipei 114, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ching-Yu","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Taipei City Hospital, Zhongxiao Branch, Taipei 11556, Taiwan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1097\/igc.0000000000000205"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-200108000-00022"},{"issue":"4","key":"3","first-page":"318","volume":"13","year":"2004","journal-title":"Nigerian Journal of Medicine"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.3238\/arztebl.2014.0877"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1007\/s13304-013-0198-z"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1097\/GCO.0b013e328359f10a"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2009.05.049"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1080\/00016340802146912"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2010.04.015"},{"issue":"3-4","key":"10","first-page":"107","volume":"6","year":"2013","journal-title":"Reviews in Obstetrics and Gynecology"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2010.06.007"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2482-14-84"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2011.12.023"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2011.02.010"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2010.10.003"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.4293\/108680813X13693422518795"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1089\/lap.2013.0103"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1089\/lap.2013.0065"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2011.03.011"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2015.09.039"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.4293\/108680810x12924466007566"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2014.08.007"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2005.03.011"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.12891\/ceog19442014"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2008.04.008"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2016\/2849476.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2016\/2849476.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2016\/2849476.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,7,26]],"date-time":"2016-07-26T10:33:44Z","timestamp":1469529224000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/bmri\/2016\/2849476\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":25,"alternative-id":["2849476","2849476"],"URL":"https:\/\/doi.org\/10.1155\/2016\/2849476","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}