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The purpose of the present study is show that metastases, although rare, must be among the differential diagnosis of skin lesions and that a diagnostic research based on these findings can be conducted. The authors report a rare case of metastatic hepatocellular injury to the scalp and skull treated by a radical surgical approach. Excision of the lesion in the scalp was performed \u201cen bloc.\u201d The tumor was supplied by the frontal branch of the superficial temporal artery. There are few case reports of metastatic HCC to scalp and skull; treatment of these lesions should be individualized in order to control symptoms, improve quality of life, and promote an increase in survival.<\/jats:p>","DOI":"10.1155\/2016\/2897048","type":"journal-article","created":{"date-parts":[[2016,6,14]],"date-time":"2016-06-14T17:03:41Z","timestamp":1465923821000},"page":"1-4","source":"Crossref","is-referenced-by-count":5,"title":["Lesion in Scalp and Skull as the First Manifestation of Hepatocellular Carcinoma"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4682-0664","authenticated-orcid":true,"given":"V. R.","family":"Ferraz","sequence":"first","affiliation":[{"name":"Neurosurgery Residency Program, Discipline of Neurosurgery, Santa Casa de Sao Paulo School of Medical Sciences, Dr. Cesario Motta Jr. 112, 01220-000 Sao Paulo, SP, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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