{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T13:19:44Z","timestamp":1788268784869,"version":"build-2803163510"},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,3,20]],"date-time":"2016-03-20T00:00:00Z","timestamp":1458432000000},"content-version":"vor","delay-in-days":79,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:p>We are presenting a case associated with papillary thyroid carcinoma, renal cell carcinoma, invasive mammary carcinoma, chondrosarcoma, benign ganglioneuroma, and numerous colon adenomas. The patient had a family history of colon cancer, kidney and bladder cancers, lung cancer, thyroid cancer, leukemia, and throat and mouth cancers. She was diagnosed with colonic villous adenoma at the age of 41 followed by thyroid, renal, and breast cancers and chondrosarcoma at the ages of 48, 64, 71, and 74, respectively. Additionally, we included a table with the most common familial cancer syndromes with one or more benign or malignant tumors diagnosed in our case, namely, FAP, HNPCC, Cowden, Peutz\u2010Jeghers, renal cancer, tuberous sclerosis, VHL, breast\/other, breast\/ovarian, Carney, Werner\u2019s, Bloom, Li\u2010Fraumeni, xeroderma pigmentosum, ataxia\u2010telangiectasia, osteochondromatosis, retinoblastoma, and MEN2A.<\/jats:p>","DOI":"10.1155\/2016\/2928084","type":"journal-article","created":{"date-parts":[[2016,3,20]],"date-time":"2016-03-20T17:01:01Z","timestamp":1458493261000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Thyroid, Renal, and Breast Carcinomas, Chondrosarcoma, Colon Adenomas, and Ganglioneuroma: A New Cancer Syndrome, FAP, or Just Coincidence"],"prefix":"10.1155","volume":"2016","author":[{"given":"Ihab Shafek","family":"Atta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahd Nasser","family":"AlQahtani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,3,20]]},"reference":[{"key":"e_1_2_5_1_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/90.14.1039"},{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/nejm199503303321302"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyv210"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01648547"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/bf00191629"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/89.23.1758"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1997.15.7.2744"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng0597-64"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng0596-114"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng0198-12"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1979.tb08070.x"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng0597-68"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.82.20.6980"},{"key":"e_1_2_5_14_2","first-page":"6639","article-title":"Fumarate hydratase-deficient cell line NCCFH1 as a new in vitro model of hereditary papillary renal cell carcinoma Type 2","volume":"35","author":"Perrier-Trudova V.","year":"2015","journal-title":"Anticancer Research"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0022-5347(01)67601-8"},{"key":"e_1_2_5_16_2","first-page":"1193","article-title":"Hereditary desmoid disease due to a frameshift mutation at codon 1924 of the APC gene","volume":"59","author":"Eccles D. 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