{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T06:17:39Z","timestamp":1789193859364,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005046","name":"Nature Science Foundation of Heilongjiang Province of China","doi-asserted-by":"crossref","award":["QC2016090"],"award-info":[{"award-number":["QC2016090"]}],"id":[{"id":"10.13039\/501100005046","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100005046","name":"Nature Science Foundation of Heilongjiang Province of China","doi-asserted-by":"crossref","award":["J16LN60"],"award-info":[{"award-number":["J16LN60"]}],"id":[{"id":"10.13039\/501100005046","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Science and Technology Planning Fund of Colleges and Universities of Shandong Province of China","award":["QC2016090"],"award-info":[{"award-number":["QC2016090"]}]},{"name":"Science and Technology Planning Fund of Colleges and Universities of Shandong Province of China","award":["J16LN60"],"award-info":[{"award-number":["J16LN60"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computational and Mathematical Methods in Medicine"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>This paper presents a fully automatic framework for lung segmentation, in which juxta-pleural nodule problem is brought into strong focus. The proposed scheme consists of three phases: skin boundary detection, rough segmentation of lung contour, and pulmonary parenchyma refinement. Firstly, chest skin boundary is extracted through image aligning, morphology operation, and connective region analysis. Secondly, diagonal-based border tracing is implemented for lung contour segmentation, with maximum cost path algorithm used for separating the left and right lungs. Finally, by arc-based border smoothing and concave-based border correction, the refined pulmonary parenchyma is obtained. The proposed scheme is evaluated on 45 volumes of chest scans, with volume difference (VD) <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mn fontstyle=\"italic\">11.15<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">69.63<\/mml:mn><\/mml:math>\u2009cm<jats:sup>3<\/jats:sup>, volume overlap error (VOE) <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mn fontstyle=\"italic\">3.5057<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">1.3719<\/mml:mn><\/mml:math>%, average surface distance (ASD) <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mn fontstyle=\"italic\">0.7917<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">0.2741<\/mml:mn><\/mml:math>\u2009mm, root mean square distance (RMSD) <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mn fontstyle=\"italic\">1.6957<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">0.6568<\/mml:mn><\/mml:math>\u2009mm, maximum symmetric absolute surface distance (MSD) <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mn fontstyle=\"italic\">21.3430<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn fontstyle=\"italic\">8.1743<\/mml:mn><\/mml:math>\u2009mm, and average time-cost 2 seconds per image. The preliminary results on accuracy and complexity prove that our scheme is a promising tool for lung segmentation with juxta-pleural nodules.<\/jats:p>","DOI":"10.1155\/2016\/2962047","type":"journal-article","created":{"date-parts":[[2016,11,16]],"date-time":"2016-11-16T17:36:09Z","timestamp":1479317769000},"page":"1-13","source":"Crossref","is-referenced-by-count":22,"title":["Automatic Approach for Lung Segmentation with Juxta-Pleural Nodules from Thoracic CT Based on Contour Tracing and Correction"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1755-4734","authenticated-orcid":true,"given":"Jinke","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Software Engineering, Harbin University of Science and Technology, Rongcheng, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4951-2002","authenticated-orcid":true,"given":"Haoyan","family":"Guo","sequence":"additional","affiliation":[{"name":"School of Computer Science and Technology, Harbin Institute of Technology, Weihai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2006.02.039"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1109\/42.650879"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1118\/1.598898"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2011.2171357"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2005.08.008"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1118\/1.3147146"},{"issue":"3","key":"7","first-page":"241","volume":"18","year":"1998","journal-title":"Journal of Signal Processing Systems"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/s1076-6332(03)00380-5"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/701514"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-23626-6_82"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1118\/1.3003066"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2008.04.012"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.compmedimag.2008.04.005"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.bspc.2014.03.010"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2008.02.004"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1109\/TMI.2005.851757"},{"key":"18","year":"2002"},{"issue":"285\u2013296","key":"19","first-page":"23","volume":"11","year":"1975","journal-title":"Automatica"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-199103000-00011"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.144.2.7089289"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1109\/42.929615"},{"key":"23","year":"1974"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1002\/nme.1620080303"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1023\/A:1012319418150"}],"container-title":["Computational and Mathematical Methods in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2016\/2962047.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2016\/2962047.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2016\/2962047.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,11,16]],"date-time":"2016-11-16T17:36:12Z","timestamp":1479317772000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/cmmm\/2016\/2962047\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":24,"alternative-id":["2962047","2962047"],"URL":"https:\/\/doi.org\/10.1155\/2016\/2962047","relation":{},"ISSN":["1748-670X","1748-6718"],"issn-type":[{"value":"1748-670X","type":"print"},{"value":"1748-6718","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}