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ROS take part in the pathogenesis of keratoconus, Fuchs endothelial corneal dystrophy, and granular corneal dystrophy type 2, stimulating apoptosis of corneal cells. ROS play a role in the pathogenesis of glaucoma stimulating apoptotic and inflammatory pathways on the level of the trabecular meshwork and promoting retinal ganglion cells apoptosis and glial dysfunction in the posterior eye segment. ROS play a role in the pathogenesis of Leber\u2019s hereditary optic neuropathy and traumatic optic neuropathy. ROS induce apoptosis of human lens epithelial cells. ROS promote apoptosis of vascular and neuronal cells and stimulate inflammation and pathological angiogenesis in the course of diabetic retinopathy. ROS are associated with the pathophysiological parainflammation and autophagy process in the course of the age\u2010related macular degeneration.<\/jats:p>","DOI":"10.1155\/2016\/3164734","type":"journal-article","created":{"date-parts":[[2016,1,10]],"date-time":"2016-01-10T21:02:18Z","timestamp":1452459738000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1224,"title":["The Role of the Reactive Oxygen Species and Oxidative Stress in the Pathomechanism of the Age\u2010Related Ocular Diseases and Other Pathologies of the Anterior and Posterior Eye Segments in 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