{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T04:42:47Z","timestamp":1778560967191,"version":"3.51.4"},"reference-count":32,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Shire-Movetis NV, Belgium"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gastroenterology Research and Practice"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. The prevalence of constipation in the (German) population has been shown to be 14.9% in a telephone survey, but more detailed data are required to characterize the sociographics and clinical characteristics of persons with different types of functional constipation, either constipation-predominant irritable bowel syndrome (IBS-C) or functional constipation with or without meeting Rome criteria.<jats:italic>Methods<\/jats:italic>. Of 2239 constipated individuals identified during the telephone interview, 1037 (46.3%) were willing to provide a postal address for a questionnaire, of which 589 (56.8%) returned the questionnaire, inquiring about sociographic data, clinical symptoms, and health care behavior related to constipation, as well as health-related quality-of-life (SF12). Subgroups of functionally constipated individuals were compared.<jats:italic>Results<\/jats:italic>. More than 50% of the respondents reported a somatic comorbid condition and\/or regular medication intake that may contribute to constipation. We split the remaining individuals (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>N<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">214<\/mml:mn><\/mml:math>) into three groups, matching Rome-criteria for IBS (IBS-C,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">64<\/mml:mn><\/mml:math>) and for functional constipation (FC-R,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">36<\/mml:mn><\/mml:math>) and FC not matching Rome criteria (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn fontstyle=\"italic\">114<\/mml:mn><\/mml:math>). Nearly all sociographic and clinical characteristics were equal among them, and all individuals with constipation had similar and lowered QOL on the SF-12 physical health domain, but in IBS-C the scores were also significantly lower in comparison to FC-R and FC, in both the physical health and the mental health domain.<jats:italic>Conclusion<\/jats:italic>. Only a fraction of individuals with chronic constipation match Rome criteria for IBS-C or FC, but subgroups do not differ with respect to most other measures except quality-of-life profiles.<\/jats:p>","DOI":"10.1155\/2016\/3186016","type":"journal-article","created":{"date-parts":[[2015,12,31]],"date-time":"2015-12-31T21:04:13Z","timestamp":1451595853000},"page":"1-9","source":"Crossref","is-referenced-by-count":18,"title":["Functional Constipation and Constipation-Predominant Irritable Bowel Syndrome in the General Population: Data from the GECCO Study"],"prefix":"10.1155","volume":"2016","author":[{"given":"Paul","family":"Enck","sequence":"first","affiliation":[{"name":"Department of Internal Medicine VI, University Hospital T\u00fcbingen, 72076 Tuebingen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Leinert","sequence":"additional","affiliation":[{"name":"infas Institut, 53113 Bonn, 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