{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T02:38:25Z","timestamp":1761964705717,"version":"3.37.3"},"reference-count":15,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Otolaryngology"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>Heerfordt\u2019s syndrome is a rare manifestation of sarcoidosis characterized by the presence of facial nerve palsy, parotid gland enlargement, anterior uveitis, and low grade fever. Two cases of Heerfordt\u2019s syndrome and a literature review are presented.<jats:italic>Case\u2009\u20091<\/jats:italic>. A 53-year-old man presented with swelling of his right eyelid, right facial nerve palsy, and swelling of his right parotid gland. A biopsy specimen from the swollen eyelid indicated sarcoidosis and he was diagnosed with incomplete Heerfordt\u2019s syndrome based on the absence of uveitis. His symptoms were improved by corticosteroid therapy.<jats:italic>Case\u2009\u20092<\/jats:italic>. A 55-year-old woman presented with left facial nerve palsy, bilateral hearing loss, and swelling of her bilateral parotid glands. She had been previously diagnosed with uveitis and bilateral hilar lymphadenopathy. Although no histological confirmation was performed, she was diagnosed with complete Heerfordt\u2019s syndrome on the basis of her clinical symptoms. Swelling of the bilateral parotid glands and left facial nerve palsy were improved immediately by corticosteroid therapy. Sarcoidosis is a relatively uncommon disease for the otolaryngologist. However, the otolaryngologist may encounter Heerfordt\u2019s syndrome as this syndrome presents with facial nerve palsy and swelling of the parotid gland. Therefore, we otolaryngologists should diagnose and treat Heerfordt\u2019s syndrome appropriately in cooperation with pneumologists and ophthalmologists.<\/jats:p>","DOI":"10.1155\/2016\/3642735","type":"journal-article","created":{"date-parts":[[2016,1,17]],"date-time":"2016-01-17T16:01:10Z","timestamp":1453046470000},"page":"1-4","source":"Crossref","is-referenced-by-count":8,"title":["Two Cases of Heerfordt\u2019s Syndrome: A Rare Manifestation of Sarcoidosis"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4770-3227","authenticated-orcid":true,"given":"Keishi","family":"Fujiwara","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Hokkaido University, N15W7, Kita-ku, Sapporo 0608638, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushi","family":"Furuta","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Teine-Keijinkai Hospital, 12-1-40 Maeda 1-Jo, Teine-Ku, Sapporo 0068555, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Fukuda","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Hokkaido University, N15W7, Kita-ku, Sapporo 0608638, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","first-page":"254","volume":"70","year":"1909","journal-title":"Archives of Ophthalmology"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1111\/j.0954-6820.1937.tb16029.x"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00025011"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1056\/nejmicm1303454"},{"issue":"4","key":"5","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1080\/08998280.2013.11929014","volume":"26","year":"2013","journal-title":"Proceedings (Baylor University Medical Center)"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1007\/s003300100879"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1017\/s0022215100062605"},{"issue":"1","key":"8","first-page":"89","volume":"27","year":"2006","journal-title":"The Japanese Journal of Sarcoidosis and Other Granulomatous Disorders"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1097\/wco.0b013e3283608459"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2008.151977"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/s1474-4422(04)00805-1"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1177\/000348948409300421"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awf027"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1997.00440370104011"},{"issue":"2","key":"15","first-page":"115","volume":"14","year":"1997","journal-title":"Sarcoidosis Vasculitis and Diffuse Lung Disease"}],"container-title":["Case Reports in Otolaryngology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criot\/2016\/3642735.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criot\/2016\/3642735.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criot\/2016\/3642735.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,3]],"date-time":"2019-09-03T15:29:04Z","timestamp":1567524544000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/criot\/2016\/3642735\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":15,"alternative-id":["3642735","3642735"],"URL":"https:\/\/doi.org\/10.1155\/2016\/3642735","relation":{},"ISSN":["2090-6765","2090-6773"],"issn-type":[{"type":"print","value":"2090-6765"},{"type":"electronic","value":"2090-6773"}],"subject":[],"published":{"date-parts":[[2016]]}}}