{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T11:07:09Z","timestamp":1751368029958},"reference-count":8,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Canadian Respiratory Journal"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>Pulmonary eosinophilia (PE) can be found in very diverse pathological processes. Several medications have also been associated with this entity. Acetaminophen is a medication commonly used in multiple different drug formulations, many of which are available without a prescription. It has however been associated with pulmonary eosinophilia (eosinophilic pneumonia) in a few cases in Japan. We describe the case of a 68-year-old Caucasian female who presented with new persistent dry cough and dyspnea on exertion after she started using up to 4 grams of acetaminophen on a daily basis. Chest imaging revealed peripheral lower lung zone ground glass and reticular opacities, and increased eosinophils were present on bronchoalveolar lavage (BAL). The patient\u2019s symptoms markedly improved upon acetaminophen cessation, and significantly decreased eosinophils were seen on repeat BAL. To our knowledge, this is the first case of likely acetaminophen-induced pulmonary eosinophilia reported outside Japan.<\/jats:p>","DOI":"10.1155\/2016\/4287270","type":"journal-article","created":{"date-parts":[[2016,3,15]],"date-time":"2016-03-15T07:57:03Z","timestamp":1458028623000},"page":"1-4","source":"Crossref","is-referenced-by-count":5,"title":["Acetaminophen Use: An Unusual Cause of Drug-Induced Pulmonary Eosinophilia"],"prefix":"10.1155","volume":"2016","author":[{"given":"Mathieu D.","family":"Saint-Pierre","sequence":"first","affiliation":[{"name":"Division of Respirology and Critical Care Medicine, Department of Medicine, Queen\u2019s University, Kingston, ON, Canada K7L 2V6"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Onofre","family":"Moran-Mendoza","sequence":"additional","affiliation":[{"name":"Division of Respirology and Critical Care Medicine, Department of Medicine, Queen\u2019s University, Kingston, ON, Canada K7L 2V6"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201202-0320st"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.216.3.r00se01773"},{"issue":"7","key":"4","first-page":"1322","volume":"30","year":"1992","journal-title":"Nihon Kyobu Gakkai Zasshi"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1378\/chest.104.1.291"},{"issue":"12","key":"6","first-page":"1585","volume":"31","year":"1993","journal-title":"Nihon Kyobu Gakkai Zasshi"},{"issue":"9","key":"7","first-page":"974","volume":"35","year":"1997","journal-title":"Nihon Kyobu Gakkai Zasshi"},{"issue":"11","key":"8","first-page":"973","volume":"36","year":"1998","journal-title":"Nihon Kyobu Gakkai Zasshi"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.iac.2012.08.007"}],"container-title":["Canadian Respiratory Journal"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crj\/2016\/4287270.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crj\/2016\/4287270.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crj\/2016\/4287270.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,18]],"date-time":"2016-08-18T20:02:24Z","timestamp":1471550544000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crj\/2016\/4287270\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":8,"alternative-id":["4287270","4287270"],"URL":"https:\/\/doi.org\/10.1155\/2016\/4287270","relation":{},"ISSN":["1198-2241","1916-7245"],"issn-type":[{"value":"1198-2241","type":"print"},{"value":"1916-7245","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}