{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T13:19:40Z","timestamp":1788268780398,"version":"build-2803163510"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,7,18]],"date-time":"2016-07-18T00:00:00Z","timestamp":1468800000000},"content-version":"vor","delay-in-days":199,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:p>\n                    <jats:italic>Background<\/jats:italic>\n                    . The presence of ulcerative colitis (UC) with no bowel symptoms, as fever of unknown origin (FUO), is uncommon.\n                    <jats:italic>Objective<\/jats:italic>\n                    . To describe the case of an 80\u2010year\u2010old woman who presented with fever, with a history of UC under treatment with mesalazine.\n                    <jats:italic>Case Presentation<\/jats:italic>\n                    . She was admitted due to fever lasting for 12 days with no associated symptoms. Seven years earlier, she was diagnosed with UC. After an extended workup for FUO that failed to reach the diagnosis, she underwent a gallium\u201067 scintigraphy. This revealed a persistent diffuse concentration of gallium\u201067 in the ascending colon at 24\u2010hour imaging that remained stable at 48\u2010 and 72\u2010hour imaging without any topographic change after the use of laxatives. Considering the results and in the absence of another diagnosis, the patient was treated with 30\u2009mg prednisone daily and mesalazine, as treatment of active UC. Subsequently, the patient\u2019s condition improved markedly and the fever retreated. One month later, she was reevaluated with a gallium\u201067 scintigraphy with total absence of gallium\u201067 concentration in the ascending colon.\n                    <jats:italic>Conclusion<\/jats:italic>\n                    . UC activity must be included in the differential diagnosis of FUO in patients with longstanding disease, since fever may present alone, with no other manifestations.\n                  <\/jats:p>","DOI":"10.1155\/2016\/4396256","type":"journal-article","created":{"date-parts":[[2016,7,18]],"date-time":"2016-07-18T17:20:26Z","timestamp":1468862426000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Ulcerative Colitis Activity Presenting as Fever of Unknown Origin, in a Patient with Longstanding Disease under Continuous Treatment with Mesalazine"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4505-5879","authenticated-orcid":false,"given":"Panagiota","family":"Voukelatou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elissavet","family":"Sfendouraki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodoros","family":"Karianos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"Saranti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios","family":"Tsitsimelis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioannis","family":"Vrettos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Kalliakmanis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,7,18]]},"reference":[{"key":"e_1_2_6_1_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.9.1033"},{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/md.0b013e31802fe858"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c5470"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.5.545"},{"key":"e_1_2_6_5_2","first-page":"2223","article-title":"Approach to the adult patient with fever of unknown origin","volume":"68","author":"Roth A. 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