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With the new nonlinear function used in the log-companding technology, this proposed amplifier has a very small total harmonic distortion (THD) and simultaneously a wide output current range. Furthermore, a differential structure with conventionally symmetrical configuration has been adopted in this novel method in order to obtain a high CMRR. Because all transistors in this amplifier operate in the weak inversion, the supply voltage and the total power consumption are significantly reduced. The novel log-companding amplifier was designed using a 0.18\u2009<jats:italic>\u03bc<\/jats:italic>m CMOS technology. Improvements in THD, output current range, noise, and CMRR are verified using simulation data. The proposed amplifier operates from a 0.8\u2009V supply voltage, shows a 6.3\u2009<jats:italic>\u03bc<\/jats:italic>A maximum output current range, and has a 6\u2009<jats:italic>\u03bc<\/jats:italic>W power consumption. The THD is less than 0.03%, the CMRR of this circuit is 74\u2009dB, and the input referred current noise density is<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mn fontstyle=\"italic\">166.1<\/mml:mn><mml:mo>\u2009<\/mml:mo><mml:mtext>fA<\/mml:mtext><mml:mo>\/<\/mml:mo><mml:msqrt><mml:mtext>Hz<\/mml:mtext><\/mml:msqrt><\/mml:math>. This new method is suitable for biomedical applications such as electrocardiogram (ECG) signal acquisition.<\/jats:p>","DOI":"10.1155\/2016\/5358963","type":"journal-article","created":{"date-parts":[[2016,9,19]],"date-time":"2016-09-19T21:01:46Z","timestamp":1474318906000},"page":"1-7","source":"Crossref","is-referenced-by-count":0,"title":["A Novel Differential Log-Companding Amplifier for Biosignal Sensing"],"prefix":"10.1155","volume":"2016","author":[{"given":"Zigang","family":"Dong","sequence":"first","affiliation":[{"name":"Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 1068 Xueyuan Road, Xili, Nanshan, Shenzhen, Guangdong 518055, China"},{"name":"Key Laboratory for Health Informatics of the Chinese Academy of Sciences (HICAS), 1068 Xueyuan Road, Xili, Nanshan, Shenzhen, Guangdong 518055, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3632-7382","authenticated-orcid":true,"given":"Xiaolin","family":"Zhou","sequence":"additional","affiliation":[{"name":"Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 1068 Xueyuan Road, Xili, Nanshan, Shenzhen, Guangdong 518055, China"},{"name":"Key Laboratory for Health Informatics of the Chinese Academy of Sciences (HICAS), 1068 Xueyuan Road, Xili, Nanshan, Shenzhen, Guangdong 518055, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuanting","family":"Zhang","sequence":"additional","affiliation":[{"name":"Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 1068 Xueyuan Road, Xili, Nanshan, Shenzhen, Guangdong 518055, China"},{"name":"Key Laboratory for Health Informatics of the Chinese Academy of Sciences (HICAS), 1068 Xueyuan Road, Xili, Nanshan, Shenzhen, Guangdong 518055, China"},{"name":"Department of Electronic Engineering, The Chinese University of Hong Kong, Shatin, Hong Kong"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1109\/82.554425"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1109\/TCSI.2005.853256"},{"year":"2007","key":"4"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1109\/TCSI.2004.835027"},{"year":"2003","key":"6"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1007\/BF01239381"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1109\/tbcas.2014.2325907"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1109\/TBCAS.2013.2256422"}],"container-title":["Journal of Sensors"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/js\/2016\/5358963.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/js\/2016\/5358963.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/js\/2016\/5358963.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,17]],"date-time":"2020-05-17T05:42:55Z","timestamp":1589694175000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/js\/2016\/5358963\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":8,"alternative-id":["5358963","5358963"],"URL":"https:\/\/doi.org\/10.1155\/2016\/5358963","relation":{},"ISSN":["1687-725X","1687-7268"],"issn-type":[{"type":"print","value":"1687-725X"},{"type":"electronic","value":"1687-7268"}],"subject":[],"published":{"date-parts":[[2016]]}}}