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Patients typically present with signs and symptoms of early pregnancy, and physicians most often suspect nonmolar pregnancy complications initially; however a hydatidiform mole should be included in the differential diagnosis of a woman with a positive pregnancy test and abnormal vaginal bleeding irrespective of the use of contraception. Our case is that of an adolescent female on Depo-Provera injectable contraceptive with increased vaginal bleeding, abdominal pain, nausea, and vomiting who was incidentally found to be pregnant and subsequently diagnosed with a molar pregnancy despite persistent denial of having initiated sexual intercourse. Though gestational trophoblastic disease is uncommon with an incidence of about 1-2 cases per 1,000 pregnancies, a clinician has to display a high index of suspicion when dealing with patients at extremes of age in order to avoid potentially life-threatening outcomes.<\/jats:p>","DOI":"10.1155\/2016\/6075049","type":"journal-article","created":{"date-parts":[[2016,12,25]],"date-time":"2016-12-25T16:04:47Z","timestamp":1482681887000},"page":"1-4","source":"Crossref","is-referenced-by-count":1,"title":["Incidental Finding of Persistent Hydatidiform Mole in an Adolescent on Depo-Provera"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7331-4479","authenticated-orcid":true,"given":"Olukayode","family":"Akinlaja","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of Tennessee College of Medicine, Chattanooga, TN, 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