{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T17:58:38Z","timestamp":1792605518606,"version":"4.5.0"},"reference-count":19,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Dentistry"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>Medication-related osteonecrosis of the jaws (MRONJ) can be considered an inability of the alveolar bone to respond to an injury, which frequently leads to severe local and systemic complications. Once the problem is installed, dentist must use all therapeutic approaches recommended. This manuscript reports a successful management of MRONJ handled with antibiotics, conservative debridement, low-level laser therapy (LLLT), and photodynamic therapy (PDT) up to 12 months. As healing of MRONJ may be very slow, combined therapeutic approaches are required. Besides the recommended conventional treatment protocol, LLLT and PDT are important tools to contribute to healing and improvement of patient\u2019s quality of life.<\/jats:p>","DOI":"10.1155\/2016\/6267406","type":"journal-article","created":{"date-parts":[[2016,9,7]],"date-time":"2016-09-07T17:08:26Z","timestamp":1473268106000},"page":"1-4","source":"Crossref","is-referenced-by-count":23,"title":["Medication-Related Osteonecrosis of Jaws: A Low-Level Laser Therapy and Antimicrobial Photodynamic Therapy Case Approach"],"prefix":"10.1155","volume":"2016","author":[{"given":"Mariana Comparotto","family":"Minamisako","sequence":"first","affiliation":[{"name":"Dentistry Department, Oncology Research Center, Florian\u00f3polis, SC, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2311-7837","authenticated-orcid":true,"given":"Guilherme Henrique","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Dentistry, Federal University of Santa Catarina, Florian\u00f3polis, SC, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mari\u00e1h Luz","family":"Lisboa","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Dentistry, Federal University of Santa Catarina, Florian\u00f3polis, SC, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mabel","family":"Mariela Rodr\u00edguez Cordeiro","sequence":"additional","affiliation":[{"name":"Department of Morphological Sciences, Federal University of Santa Catarina, Florian\u00f3polis, SC, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liliane Janete","family":"Grando","sequence":"additional","affiliation":[{"name":"Department of Pathology, Ambulatory of Stomatology, University Hospital, Federal University of Santa Catarina, Florian\u00f3polis, SC, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.2009.01143.x"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-014-0583-z"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2007.12.040"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2011.03713.x"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.2010.01240.x"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2014.02.011"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2014.04.031"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1039\/c3pp50325a"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.dental.2014.02.006"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8027.2007.00114.x"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1089\/pho.2005.23.70"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2004.00994.x"},{"issue":"1","key":"16","first-page":"171","volume":"137","year":"1990","journal-title":"The American Journal of Pathology"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.18812"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1089\/pho.2016.4094"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-016-3139-9"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-014-1632-2"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-014-1613-5"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2014.04.001"}],"container-title":["Case Reports in Dentistry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crid\/2016\/6267406.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crid\/2016\/6267406.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crid\/2016\/6267406.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,9,7]],"date-time":"2016-09-07T17:08:26Z","timestamp":1473268106000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crid\/2016\/6267406\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":19,"alternative-id":["6267406","6267406"],"URL":"https:\/\/doi.org\/10.1155\/2016\/6267406","relation":{},"ISSN":["2090-6447","2090-6455"],"issn-type":[{"value":"2090-6447","type":"print"},{"value":"2090-6455","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}