{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T06:10:37Z","timestamp":1768889437709,"version":"3.49.0"},"reference-count":17,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p><jats:italic>Objectives<\/jats:italic>. In this study, we aimed to demonstrate the perinatal and neonatal outcomes of patients who were diagnosed with neural tube defect (NTD) in the midtrimester fetal ultrasound scan and refused the request for termination of pregnancy.<jats:italic> Material and Methods<\/jats:italic>. The records of 69 patients, for whom NTD was detected in the midtrimester fetal ultrasound scan and who preferred the continuation of the pregnancy after comprehensive counselling about the possible prognosis and treatment options during the period between January 2011 and February 2016, were reviewed retrospectively.<jats:italic> Results<\/jats:italic>. Of these patients, 66.7% were 25\u201335 years old; 95.7% were multiparous; and 1.4% had a history of a fetus having NTD in previous pregnancies. There were 7 (10.1%) neonatal deaths in these patients. Meningomyelocele closure procedure was the most performed surgery in the postnatal period (92%). Of these patients, 30.7% had paraplegia; 51.6% had neurogenic bladder; and 6.4% had infections due to surgery.<jats:italic> Conclusion<\/jats:italic>. The results of this study demonstrated perinatal and neonatal outcomes of fetuses with NTD who were not terminated by the preference of the family in midtrimester. The experience of our centre would be beneficial as a tool for nondirective counselling of these patients when considering the antenatal\/postnatal care options and postnatal prognosis.<\/jats:p>","DOI":"10.1155\/2016\/6382825","type":"journal-article","created":{"date-parts":[[2016,11,23]],"date-time":"2016-11-23T16:08:30Z","timestamp":1479917310000},"page":"1-6","source":"Crossref","is-referenced-by-count":3,"title":["Perinatal and Neonatal Outcomes of Patients Who Were Diagnosed with Neural Tube Defect in Midtrimester Fetal Ultrasound Scan and Refused Request for Termination of Pregnancy"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7113-6691","authenticated-orcid":true,"given":"Rauf","family":"Melekoglu","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Inonu, 44280 Malatya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sevil","family":"Eraslan","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Inonu, 44280 Malatya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ebru","family":"Celik","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine, The University of Inonu, 44280 Malatya, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yavuz","family":"Simsek","sequence":"additional","affiliation":[{"name":"Private Clinic of Yavuz Simsek, 71200 K\u0131r\u0131kkale, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20778"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000178780.63956.3b"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2273020535"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2013.10.006"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1159\/000056005"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1159\/000264297"},{"issue":"4","key":"7","first-page":"359","volume":"55","year":"2013","journal-title":"Turkish Journal of Pediatrics"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(86)91610-7"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(90)90378-k"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.3109\/01443615.2013.834307"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20062"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1002\/pd.1378"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.33886"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1515\/jpm-2015-0364"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(98)70278-9"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/s1701-2163(15)30444-8"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1014379"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2016\/6382825.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2016\/6382825.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2016\/6382825.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,11,23]],"date-time":"2016-11-23T16:08:30Z","timestamp":1479917310000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/bmri\/2016\/6382825\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":17,"alternative-id":["6382825","6382825"],"URL":"https:\/\/doi.org\/10.1155\/2016\/6382825","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}