{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:49:24Z","timestamp":1787168964607,"version":"build-2736575974"},"reference-count":44,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Bangladesh Medical Research Council","award":["12-237 RG\/PHA\/AS_C"],"award-info":[{"award-number":["12-237 RG\/PHA\/AS_C"]}]},{"name":"Bangladesh Medical Research Council","award":["14-385 RG\/PHA\/AS_C"],"award-info":[{"award-number":["14-385 RG\/PHA\/AS_C"]}]},{"DOI":"10.13039\/501100002222","name":"The World Academy of Sciences","doi-asserted-by":"publisher","award":["12-237 RG\/PHA\/AS_C"],"award-info":[{"award-number":["12-237 RG\/PHA\/AS_C"]}],"id":[{"id":"10.13039\/501100002222","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002222","name":"The World Academy of Sciences","doi-asserted-by":"publisher","award":["14-385 RG\/PHA\/AS_C"],"award-info":[{"award-number":["14-385 RG\/PHA\/AS_C"]}],"id":[{"id":"10.13039\/501100002222","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002222","name":"The World Academy of Sciences","doi-asserted-by":"publisher","award":["12-237 RG\/PHA\/AS_C"],"award-info":[{"award-number":["12-237 RG\/PHA\/AS_C"]}],"id":[{"id":"10.13039\/501100002222","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002222","name":"The World Academy of Sciences","doi-asserted-by":"publisher","award":["14-385 RG\/PHA\/AS_C"],"award-info":[{"award-number":["14-385 RG\/PHA\/AS_C"]}],"id":[{"id":"10.13039\/501100002222","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>The present study was designed to investigate the cardioprotective effects of Sundarban honey (SH) in rats with isoproterenol- (ISO-) induced myocardial infarction. Adult male Wistar Albino rats were pretreated with Sundarban honey (5\u2009g\/kg) daily for a period of 6 weeks. After the treatment period, ISO (85\u2009mg\/kg) was subcutaneously injected into the rats at 24\u2009h intervals for 2 days. ISO-induced myocardial damage was indicated by increased serum cardiac specific troponin I levels and cardiac marker enzyme activities including creatine kinase-MB, lactate dehydrogenase, aspartate transaminase, and alanine transaminase. Significant increases in serum total cholesterol, triglycerides, and low-density lipoprotein-cholesterol levels were also observed, along with a reduction in the serum high-density lipoprotein-cholesterol level. In addition to these diagnostic markers, the levels of lipid peroxide products were significantly increased. The activities of antioxidant enzymes such as superoxide dismutase, glutathione peroxidase, and glutathione reductase were significantly decreased in the hearts after ISO-induced myocardial infarction. However, pretreatment of ischemic rats with Sundarban honey brought the biochemical parameters to near normalcy, indicating the protective effect of Sundarban honey against ISO-induced ischemia in rats. Histopathological findings of the heart tissues further confirmed the biochemical findings, indicating that Sundarban honey confers protection against ISO-induced oxidative stress in the myocardium.<\/jats:p>","DOI":"10.1155\/2016\/6437641","type":"journal-article","created":{"date-parts":[[2016,5,17]],"date-time":"2016-05-17T17:03:48Z","timestamp":1463504628000},"page":"1-10","source":"Crossref","is-referenced-by-count":38,"title":["Sundarban Honey Confers Protection against Isoproterenol-Induced Myocardial Infarction in Wistar Rats"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1108-3406","authenticated-orcid":true,"given":"Rizwana","family":"Afroz","sequence":"first","affiliation":[{"name":"Laboratory of Preventive and Integrative Biomedicine, Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka 1342, Bangladesh"},{"name":"Department of Biochemistry, Primeasia University, Banani, Dhaka 1213, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5867-7004","authenticated-orcid":true,"given":"E. M.","family":"Tanvir","sequence":"additional","affiliation":[{"name":"Laboratory of Preventive and Integrative Biomedicine, Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka 1342, Bangladesh"},{"name":"Department of Biochemistry and Molecular Biology, Gonoshasthaya Samaj Vittik Medical College, Gono University, Mirzanagar, Savar, Dhaka 1344, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nurul","family":"Karim","sequence":"additional","affiliation":[{"name":"Laboratory of Preventive and Integrative Biomedicine, Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka 1342, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Md. Sabir","family":"Hossain","sequence":"additional","affiliation":[{"name":"Laboratory of Preventive and Integrative Biomedicine, Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka 1342, Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Alam","sequence":"additional","affiliation":[{"name":"Human Genome Centre, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6470-3651","authenticated-orcid":true,"given":"Siew Hua","family":"Gan","sequence":"additional","affiliation":[{"name":"Human Genome Centre, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8358-0252","authenticated-orcid":true,"given":"Md. Ibrahim","family":"Khalil","sequence":"additional","affiliation":[{"name":"Laboratory of Preventive and Integrative Biomedicine, Department of Biochemistry and Molecular Biology, Jahangirnagar University, Savar, Dhaka 1342, Bangladesh"},{"name":"Human Genome Centre, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"issue":"6","key":"1","first-page":"7","volume":"2","year":"2013","journal-title":"International Research Journal of Social Science"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/143782"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.eujim.2015.04.004"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2006.11.053"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/0033-0620(90)90039-5"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/s2222-1808(14)60474-6"},{"key":"7","first-page":"115","volume-title":"Electrophysiological responses to ischemia and reperfusion","year":"1996"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(96)07492-2"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2828(85)80130-9"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1139\/y82-207"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/624159"},{"issue":"2","key":"12","first-page":"113","volume":"36","year":"1982","journal-title":"Acta Medica Okayama"},{"issue":"10","key":"13","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.1351\/pac200274101957","volume":"74","year":"2002","journal-title":"Pure and Applied Chemistry"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6882-12-177"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1111\/jfbc.12240"},{"key":"16","first-page":"166","volume":"4","year":"2005","journal-title":"Natural Product Radiance"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/j.etp.2008.03.010"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1016\/j.etp.2011.01.012"},{"issue":"6","key":"19","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/clinchem\/18.6.499","volume":"18","year":"1972","journal-title":"Clinical Chemistry"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(79)90738-3"},{"issue":"1","key":"21","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","volume":"193","year":"1951","journal-title":"The Journal of Biological Chemistry"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1007\/s11130-008-0105-9"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1016\/s0735-1097(00)00804-4"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2008.12.012"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2004.03.004"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2010.06.065"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1079\/nrr19960013"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1016\/s0891-5849(99)00055-6"},{"issue":"2","key":"29","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0022-2275(20)32053-8","volume":"41","year":"2000","journal-title":"Journal of Lipid Research"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2012.07.067"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.85.1.22"},{"key":"32","first-page":"2593","volume":"4","year":"2014","journal-title":"Indo American Journal of Pharmaceutical Research"},{"issue":"1","key":"33","first-page":"39","volume":"26","year":"2011","journal-title":"Nigerian Journal of Physiological Sciences"},{"issue":"2","key":"34","first-page":"161","volume":"26","year":"2011","journal-title":"Nigerian Journal of Physiological Sciences"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.3390\/molecules16065054"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1016\/0925-4439(95)00083-g"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-199549030-00003"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1016\/0020-711X(84)90167-8"},{"issue":"2","key":"39","first-page":"161","volume":"14","year":"2009","journal-title":"Alternative Medicine Review"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2011.09.005"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/286051"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.1016\/0047-6374(90)90078-T"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1128\/mcb.01080-08"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2011.08.616"}],"updated-by":[{"DOI":"10.1155\/bmri\/9787512","type":"retraction","label":"Retraction","source":"publisher","updated":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000}}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2016\/6437641.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2016\/6437641.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2016\/6437641.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,24]],"date-time":"2022-06-24T10:50:11Z","timestamp":1656067811000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/bmri\/2016\/6437641\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":44,"alternative-id":["6437641","6437641"],"URL":"https:\/\/doi.org\/10.1155\/2016\/6437641","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}