{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T20:45:30Z","timestamp":1790369130932,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81170265"],"award-info":[{"award-number":["81170265"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81360055"],"award-info":[{"award-number":["81360055"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81460081"],"award-info":[{"award-number":["81460081"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81170265"],"award-info":[{"award-number":["81170265"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81360055"],"award-info":[{"award-number":["81360055"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81460081"],"award-info":[{"award-number":["81460081"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81170265"],"award-info":[{"award-number":["81170265"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81360055"],"award-info":[{"award-number":["81360055"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81460081"],"award-info":[{"award-number":["81460081"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Disease Markers"],"published-print":{"date-parts":[[2016]]},"abstract":"\n Background<\/jats:italic>\n . Recent evidence demonstrated that the circulating levels of omentin-1 are related to the presence of ischemic heart disease and heart failure. However, omentin-1 plasma levels in patients with nonischemic dilated cardiomyopathy (DCM), which is the most common etiology of heart failure, have yet to be investigated.\n Methods<\/jats:italic>\n . Plasma levels of omentin-1 and adiponectin were measured in 100 patients with DCM and 45 healthy controls.\n Results<\/jats:italic>\n . Plasma omentin-1 levels significantly decreased in DCM patients compared with the control group, whereas adiponectin levels significantly increased in DCM patients compared with the control group. Plasma omentin-1 levels were negatively correlated with adiponectin (\n \n R<\/mml:mi>\n =<\/mml:mo>\n -<\/mml:mo>\n 0.376<\/mml:mn>\n <\/mml:math>\n ,\n \n P<\/mml:mi>\n =<\/mml:mo>\n 0.005<\/mml:mn>\n <\/mml:math>\n ), C-reactive protein (CRP) (\n \n R<\/mml:mi>\n =<\/mml:mo>\n -<\/mml:mo>\n 0.320<\/mml:mn>\n <\/mml:math>\n ,\n \n P<\/mml:mi>\n =<\/mml:mo>\n 0.001<\/mml:mn>\n <\/mml:math>\n ), and N-terminal pro-brain natriuretic peptide (NT-proBNP) (\n \n R<\/mml:mi>\n =<\/mml:mo>\n -<\/mml:mo>\n 0.365<\/mml:mn>\n <\/mml:math>\n ,\n \n P<\/mml:mi>\n =<\/mml:mo>\n 0.000<\/mml:mn>\n <\/mml:math>\n ) levels as well as left ventricular end-diastolic diameter (LVEDD) (\n \n R<\/mml:mi>\n =<\/mml:mo>\n -<\/mml:mo>\n 0.200<\/mml:mn>\n <\/mml:math>\n ,\n \n P<\/mml:mi>\n =<\/mml:mo>\n 0.046<\/mml:mn>\n <\/mml:math>\n ) but were positively correlated with left ventricular ejection fraction (LVEF) (\n \n R<\/mml:mi>\n =<\/mml:mo>\n 0.496<\/mml:mn>\n <\/mml:math>\n ,\n \n P<\/mml:mi>\n =<\/mml:mo>\n 0.000<\/mml:mn>\n <\/mml:math>\n ). Plasma adiponectin levels were positively correlated with CRP (\n \n R<\/mml:mi>\n =<\/mml:mo>\n 0.273<\/mml:mn>\n <\/mml:math>\n ,\n \n P<\/mml:mi>\n =<\/mml:mo>\n 0.006<\/mml:mn>\n <\/mml:math>\n ) and NT-proBNP (\n \n R<\/mml:mi>\n =<\/mml:mo>\n 0.329<\/mml:mn>\n <\/mml:math>\n ,\n \n P<\/mml:mi>\n =<\/mml:mo>\n 0.001<\/mml:mn>\n <\/mml:math>\n ) levels but were negatively correlated with fasting glucose (\n \n R<\/mml:mi>\n =<\/mml:mo>\n -<\/mml:mo>\n 0.218<\/mml:mn>\n <\/mml:math>\n ,\n \n P<\/mml:mi>\n =<\/mml:mo>\n 0.029<\/mml:mn>\n <\/mml:math>\n ) and LVEF (\n \n R<\/mml:mi>\n =<\/mml:mo>\n -<\/mml:mo>\n 0.615<\/mml:mn>\n <\/mml:math>\n ,\n \n P<\/mml:mi>\n =<\/mml:mo>\n 0.000<\/mml:mn>\n <\/mml:math>\n ) levels. Furthermore, omentin-1 (OR 0.983, 95% CI 0.970 to 0.996;\n \n P<\/mml:mi>\n =<\/mml:mo>\n 0.008<\/mml:mn>\n <\/mml:math>\n ) levels were independently associated with the presence of DCM before NT-proBNP was added.\n Conclusions<\/jats:italic>\n . Omentin-1 is a novel biomarker of DCM.\n <\/jats:p>","DOI":"10.1155\/2016\/6762825","type":"journal-article","created":{"date-parts":[[2016,5,24]],"date-time":"2016-05-24T17:31:36Z","timestamp":1464111096000},"page":"1-7","source":"Crossref","is-referenced-by-count":20,"title":["Circulating Omentin-1 Levels Are Decreased in Dilated Cardiomyopathy Patients with Overt Heart Failure"],"prefix":"10.1155","volume":"2016","author":[{"given":"Ying","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Cardiology, The People\u2019s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingzhong","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The People\u2019s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shumin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, The People\u2019s Hospital of Juxian, Juxian 276500, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhijian","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung, and Blood Vessel Disease, The Key Laboratory of Remodeling-Related Cardiovascular Disease, Ministry of Education, Beijing 100029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianwei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung, and Blood Vessel Disease, The Key Laboratory of Remodeling-Related Cardiovascular Disease, Ministry of Education, Beijing 100029, 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