{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T21:17:07Z","timestamp":1775942227060,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Endocrinology"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p><jats:italic>Objectives<\/jats:italic>. The aim of our study was to investigate the differences in adrenal gland volume between nondiabetic controls and Type-2 diabetic patients and to examine the influence of glycemic control in diabetes mellitus on adrenal gland volume.<jats:italic>Methods<\/jats:italic>. From March 2 to November 25, 2015, 62 consecutive patients with Type-2 DM along with 62 nondiabetics matched by age, gender, and BMI were enrolled in this prospective study. Our diabetes patients were categorized into two groups, well-controlled and poorly controlled diabetes groups. Adrenal volumetric measurements were performed by two radiologists, prospectively and independently, with semiautomatic software. Interobserver reliability was studied using the interobserver correlation coefficient (ICC).<jats:italic>Results<\/jats:italic>. The total adrenal volume (TAV) was significantly higher in Type-2 diabetic patients when compared with nondiabetic patients (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.05<\/mml:mn><\/mml:math>). When we investigated diabetic patients according to glycemic controls, the TAVs in controlled diabetic patients were significantly higher than in those of the poorly controlled or uncontrolled diabetic patients (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.05<\/mml:mn><\/mml:math>). Nondiabetic control patients have significantly smaller TAVs when compared to controlled and poorly or noncontrolled diabetic patients (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn fontstyle=\"italic\">0.05<\/mml:mn><\/mml:math>).<jats:italic>Conclusion<\/jats:italic>. Our study suggests that adrenal gland volume measurement may be used as an indirect marker of glycemic control in patients with diabetes.<\/jats:p>","DOI":"10.1155\/2016\/7195849","type":"journal-article","created":{"date-parts":[[2016,8,2]],"date-time":"2016-08-02T20:17:33Z","timestamp":1470169053000},"page":"1-5","source":"Crossref","is-referenced-by-count":9,"title":["The Adrenal Gland Volume Measurements in Manifestation of the Metabolic Status in Type-2 Diabetes Mellitus Patients"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5643-739X","authenticated-orcid":true,"given":"Ismail","family":"Serifoglu","sequence":"first","affiliation":[{"name":"Department of Radiology, Bagcilar Training and Research Hospital, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5014-4972","authenticated-orcid":true,"given":"Ibrahim Ilker","family":"Oz","sequence":"additional","affiliation":[{"name":"Department of Radiology, Bulent Ecevit University School of Medicine, Zonguldak, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8678-4605","authenticated-orcid":true,"given":"Muammer","family":"Bilici","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Bulent Ecevit University School of Medicine, Zonguldak, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2006-2674"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-011-9585-2"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-015-4063-y"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2014.06.008"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1007\/BF03344090"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.84.9.5953"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00389.2004"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2015.04.008"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00674.2004"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1186\/2251-6581-12-9"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.51.6.1681"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.2337\/dc11-s011"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/s0006-8993(02)04091-x"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1159\/000087034"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresbull.2008.07.001"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1159\/000283560"},{"issue":"4","key":"17","first-page":"482","volume":"29","year":"2004","journal-title":"Abdominal Imaging"}],"container-title":["International Journal of Endocrinology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/ije\/2016\/7195849.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ije\/2016\/7195849.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/ije\/2016\/7195849.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,2]],"date-time":"2016-08-02T20:17:33Z","timestamp":1470169053000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/ije\/2016\/7195849\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":17,"alternative-id":["7195849","7195849"],"URL":"https:\/\/doi.org\/10.1155\/2016\/7195849","relation":{},"ISSN":["1687-8337","1687-8345"],"issn-type":[{"value":"1687-8337","type":"print"},{"value":"1687-8345","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}