{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T02:07:37Z","timestamp":1745978857078,"version":"3.37.3"},"reference-count":26,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anesthesiology Research and Practice"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p><jats:italic>Purpose<\/jats:italic>. Failed back surgery syndrome is a chronic pain condition requiring rapid, effective, and efficient management. This study evaluates the effect of adding dexmedetomidine to lumbar epidural steroids in patients with failed back surgery syndrome.<jats:italic>Methods<\/jats:italic>. Fifty patients suffering from failed back surgery syndrome were randomly assigned to one of two groups, receiving an epidural injection of 20\u2009mL of either a mixture of betamethasone (14\u2009mg) and bupivacaine 0.5\u2009mg (group C) or a mixture of betamethasone (14\u2009mg), bupivacaine 0.5\u2009mg, and dexmedetomidine (0.5\u2009<jats:italic>\u03bc<\/jats:italic>g\/kg) (group D) adjusted to the volume with normal saline. The effect was evaluated using visual analogue scale (VAS), analgesic requirement, and Oswestry disability index 2 weeks, 4 weeks, 8 weeks, and 12 weeks after injection.<jats:italic>Results<\/jats:italic>. VAS and ibuprofen consumption showed a significant reduction in group D. The Oswestry disability index was significantly improved in group D. There were no records of hypotension, bradycardia, sedation, or hypoxemia in both groups.<jats:italic>Conclusion<\/jats:italic>. The present study demonstrated potential safe and effective usage of adding dexmedetomidine to epidural steroid to control pain in patients with failed back surgery syndrome.<\/jats:p>","DOI":"10.1155\/2016\/7198048","type":"journal-article","created":{"date-parts":[[2016,8,17]],"date-time":"2016-08-17T17:04:14Z","timestamp":1471453454000},"page":"1-4","source":"Crossref","is-referenced-by-count":3,"title":["The Effect of Dexmedetomidine on Lumbar Epidural Injection for Failed Back Surgery Syndrome"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5791-1855","authenticated-orcid":true,"given":"Ashraf","family":"Eskandr","sequence":"first","affiliation":[{"name":"Department of Anaesthesia, ICU and Pain Therapy, Faculty of Medicine, Menoufiya University, Shibin El-Koom 32518, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sadik","family":"Abdel Maseeh","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, ICU and Pain Therapy, Faculty of Medicine, Menoufiya University, Shibin El-Koom 32518, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.5535\/arm.2012.36.4.466"},{"key":"2","first-page":"371","volume":"28","year":"2004","journal-title":"Journal of Korean Academy of Rehabilitation Medicine"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1526-4637.2011.01089.x"},{"issue":"1","key":"4","first-page":"E75","volume":"17","year":"2014","journal-title":"Pain Physician"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1053\/rapm.2002.27175"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000134806.61887.0D"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/S0952-8180(00)00171-9"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1533-2500.2011.00469.x"},{"issue":"6","key":"9","first-page":"817","volume":"11","year":"2008","journal-title":"Pain Physician"},{"issue":"3","key":"10","first-page":"231","volume":"16","year":"2013","journal-title":"Pain Physician"},{"key":"11","first-page":"365","volume":"5","year":"2011","journal-title":"Indian Journal of Anaesthesia"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2008.01818.x"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.3410\/m2-90"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5049.79883"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.4103\/1658-354X.87264"},{"issue":"3","key":"16","first-page":"47","volume":"6","year":"2012","journal-title":"Journal of Prenatal Medicine"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aep159"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5049.84835"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aes385"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.4097\/kjae.2013.64.4.301"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.4103\/0973-1075.97354"},{"issue":"4","key":"22","first-page":"365","volume":"13","year":"2010","journal-title":"Pain Physician"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1111\/cns.12100"},{"issue":"2","key":"24","first-page":"187","volume":"17","year":"2014","journal-title":"Pain Physician"},{"issue":"4","key":"25","first-page":"373","volume":"57","year":"2006","journal-title":"Acta Anaesthesiologica Belgica"},{"issue":"1","key":"26","first-page":"34","volume":"52","year":"2002","journal-title":"Revista Brasileira de Anestesiologia"}],"container-title":["Anesthesiology Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/arp\/2016\/7198048.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/arp\/2016\/7198048.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/arp\/2016\/7198048.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,17]],"date-time":"2016-08-17T17:04:14Z","timestamp":1471453454000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/arp\/2016\/7198048\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":26,"alternative-id":["7198048","7198048"],"URL":"https:\/\/doi.org\/10.1155\/2016\/7198048","relation":{},"ISSN":["1687-6962","1687-6970"],"issn-type":[{"type":"print","value":"1687-6962"},{"type":"electronic","value":"1687-6970"}],"subject":[],"published":{"date-parts":[[2016]]}}}