{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T18:17:19Z","timestamp":1789496239153,"version":"build-2803163510"},"reference-count":14,"publisher":"Wiley","license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Canadian Journal of Infectious Diseases and Medical Microbiology"],"published-print":{"date-parts":[[2016]]},"abstract":"<jats:p>Chronic Q fever is a potentially life-threatening infection from the intracellular, Gram-negative<jats:italic>Coxiella burnetii<\/jats:italic>. It presents most commonly as endocarditis or vascular infection in people with underlying cardiac or vascular disease. We discuss a case of a 67-year-old male with<jats:italic>Coxiella burnetii<\/jats:italic>vascular infection of a perirenal abdominal aortic graft. The patient had a history of an abdominal aortic aneurysm (AAA) repair 5 years earlier. He presented with a 12 \u00d7 6 \u00d7 8\u2009cm perirenal pseudoaneurysm and concomitant L1, L2, and L3 vertebral body discitis. He underwent an open repair which revealed a grossly infected graft perioperatively. Q fever serology revealed phase I serological IgG titer of 1\u2009:\u20092048 and phase II 1\u2009:\u20091024 consistent with chronic Q fever. Polymerase chain reaction (PCR) on infected vascular tissue was positive for<jats:italic>C. burnetii<\/jats:italic>. The patient was started on doxycycline and hydroxychloroquine with good clinical response and decreasing serological titers. Recognizing chronic Q fever is a difficult task as symptoms are nonspecific, exposure risk is difficult to ascertain, and diagnosis is hidden from conventional microbiological investigations. Its recognition, however, is critical as<jats:italic>C. burnetii<\/jats:italic>is inherently resistant to standard empiric therapies used in cardiovascular infections.<\/jats:p>","DOI":"10.1155\/2016\/7456157","type":"journal-article","created":{"date-parts":[[2016,5,11]],"date-time":"2016-05-11T17:01:47Z","timestamp":1462986107000},"page":"1-3","source":"Crossref","is-referenced-by-count":12,"title":["Chronic Q Fever in Alberta: A Case of<i>Coxiella burnetii<\/i>Mycotic Aneurysm and Concomitant Vertebral Osteomyelitis"],"prefix":"10.1155","volume":"2016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8684-0494","authenticated-orcid":true,"given":"William","family":"Stokes","sequence":"first","affiliation":[{"name":"University of Calgary, Calgary, AB, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack","family":"Janvier","sequence":"additional","affiliation":[{"name":"University of Calgary, Calgary, AB, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Vaughan","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, South Health Campus, 4th Floor, Room 480073, 4448 Front Street SE, Calgary, AB, Canada T3M 1M4"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/16.2.282"},{"issue":"3","key":"2","first-page":"1","volume":"17","year":"2012","journal-title":"Eurosurveillance"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.00993-13"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1086\/515401"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1128\/cvi.05724-11"},{"key":"6","year":"2013"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/s0828-282x(06)70295-1"},{"issue":"4","key":"8","first-page":"563","volume":"18","year":"2012","journal-title":"Emerging Infectious Diseases journal"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1993.00410050074010"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2011.04.013"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2012.09.001"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2012.04.006"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2011.12.014"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.159.2.167"}],"container-title":["Canadian Journal of Infectious Diseases and Medical Microbiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjidmm\/2016\/7456157.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjidmm\/2016\/7456157.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cjidmm\/2016\/7456157.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,7,26]],"date-time":"2016-07-26T13:13:05Z","timestamp":1469538785000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/cjidmm\/2016\/7456157\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":14,"alternative-id":["7456157","7456157"],"URL":"https:\/\/doi.org\/10.1155\/2016\/7456157","relation":{},"ISSN":["1712-9532","1918-1493"],"issn-type":[{"value":"1712-9532","type":"print"},{"value":"1918-1493","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]}}}