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For this reason, along with inflammation, oxidative stress seems to be one of the main inducers of neurodegeneration, causing excitotoxicity, neuronal loss, and axonal damage, ultimately being now considered a key element in the onset and progression of several neurodegenerative diseases, including Alzheimer\u2019s disease, Parkinson\u2019s disease, amyotrophic lateral sclerosis, multiple sclerosis, and hereditary spastic paraplegia. 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